Observational cohort of patients with spondyloarthritis at Nanfang Hospital
Bidirectional Cohort Study of Nanfang Spondyloarthritis
This study is collecting health information from patients with spondyloarthritis at Nanfang Hospital to better understand the condition over time without changing their usual care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3000 (estimated) |
| Ages | 10 Years to 59 Years |
| Sex | All |
| Sponsor | Nanfang Hospital, Southern Medical University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT06988813 on ClinicalTrials.gov |
What this trial studies
This observational study aims to establish a specialized cohort of spondyloarthritis (SpA) patients at Nanfang Hospital, where clinical condition scales, laboratory indicators, and imaging data will be collected during routine follow-up visits. The cohort will archive disease characteristics, biochemical index data, and disease assessment scales without imposing any interventional treatments or additional tests on patients. Data will include disease duration, symptom characteristics, comorbidities, and various imaging results, creating a comprehensive dataset for future analysis of SpA. The study will span from 2010 to 2030, capturing both prospective and retrospective data.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 10 to 59 years with a standardized diagnosis of spondyloarthritis who have attended Nanfang Hospital between 2010 and 2025.
Not a fit: Patients who are pregnant, preparing for pregnancy, breastfeeding, or have moderate to severe heart failure will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of spondyloarthritis and improve patient management through comprehensive data collection.
How similar studies have performed: While this approach is observational and builds on existing methodologies, similar studies have shown success in establishing disease cohorts for chronic conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1.Attended Nanfang Hospital, Southern Medical University, 2010-2030 2.Prospective cohort study component: subjects voluntarily participate with informed consent and sign an informed consent form 3.Retrospective cohort study: (i) patients who visited the hospital from April 2010 to April 2024 (and who will not return to the hospital at a later date) were exempted from informed consent; (ii) patients who visited the hospital from May 2024 to April 2025 were required to sign an informed consent 4.10 years old ≤ age ≤ 59 years old 5.Patients with a standardized diagnosis of spondyloarthritis by the following guidelines or diagnostic criteria, i.e., meeting one of the following diagnostic criteria: (1) 2009 ASAS classification criteria for axial spondyloarthritis; (2) 2011 ASAS classification criteria for peripheral spondyloarthritis Exclusion Criteria: * 1\. Women who are pregnant, preparing for pregnancy or breastfeeding 2.Moderate to Severe Heart Failure (New York Heart Association Class 3-4) 3.Active peptic ulcers/bleeding 4.Judged by the investigator to be unsuitable for participation in this study
Where this trial is running
Guangzhou, Guangdong
- Nanfang Hostipal,Southern Medical University — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Jun Xiao, Dr
- Email: orthopaedxj@163.com
- Phone: 0086-20-18665000156
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.