Observational cohort for early spondyloarthritis in Germany

German Spondyloarthritis Inception Cohort

Observational Charite University, Berlin, Germany · NCT01277419

This study is tracking patients with early spondyloarthritis in Germany to see how the disease progresses and affects their quality of life over time.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
SexAll
SponsorCharite University, Berlin, Germany Academic / other
Locations1 site (Berlin)
Trial IDNCT01277419 on ClinicalTrials.gov

What this trial studies

The German Spondyloarthritis Inception Cohort (GESPIC) is a prospective, longitudinal study initiated in 2000 that focuses on patients with early spondyloarthritis, including ankylosing spondylitis and non-radiographic axial spondyloarthritis. The study aims to track the progression of the disease over time, assess outcomes such as radiographic changes, and identify predictors of these outcomes. Additionally, it evaluates the quality of life and associated costs for patients, expanding to include other related conditions like acute anterior uveitis and Crohn's disease. This multicenter study is conducted across various locations in Germany.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with axial spondyloarthritis, juvenile spondyloarthritis, Crohn's disease, acute anterior uveitis, or psoriatic arthritis with axial involvement.

Not a fit: Patients without a confirmed diagnosis of the specified conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of early spondyloarthritis and improve management strategies for patients.

How similar studies have performed: Other studies focusing on early spondyloarthritis have shown promise, indicating that this approach is supported by prior research.

Eligibility criteria

Show full inclusion / exclusion criteria
Main inclusion Criteria:

* Patients with definite diagnosis of axial spondyloarthritis or juvenile spondyloarthritis.
* Patients with definite diagnosis of Crohn's disease.
* Patients with definite diagnosis of acute anterior uveitis.
* Patients with definite diagnosis of psoriatic arthritis with axial involvement.

Where this trial is running

Berlin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ankylosing Spondylitis / Radiographic Axial SpANon-radiographic Axial SpondyloarthritisAxial Psoriatic ArthritisAcute Anterior UveitisCrohn DiseaseUlcerative Colitis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.