Nystagmus testing with wearable AR glasses in vertigo patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center, within-subject randomized equivalence study at Kaohsiung Chang Gung Memorial Hospital. Each participant undergoes both AR-based and conventional oculomotor testing in a randomized order during the same visit, with a 30-minute washout between tests. Independent experts review de-identified test trajectories offline, blinded to modality, to assess diagnostic accuracy and reliability (test-retest and inter-rater). A follow-up visit about one week later collects additional data. The intervention uses wearable AR glasses for nystagmus examination; the comparator is the standard exam performed in a traditional examination room. The study includes adults with vertigo or dizziness who can complete both testing modalities and provide consent, excluding those with recent vestibular-suppressant use, ocular conditions affecting eye tracking, photosensitive conditions, motion sickness, or cognitive limitations that would preclude participation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults ≥18 years with vertigo/dizziness suggestive of a central or peripheral vestibular disorder.
* Able to complete both AR-based and conventional oculomotor testing during the same visit (with \~30-minute washout).
* Provide written informed consent.
* Adequate vision for eye-tracking and calibration (e.g., corrected visual acuity ≥20/40 in each eye).
* Willing and able to return for the follow-up visit.

Exclusion Criteria:

* Use of vestibular-suppressant medications within 24 hours prior to testing (e.g., benzodiazepines, antihistamines, anticholinergics).
* Ocular conditions that would interfere with reliable eye tracking (e.g., corrected visual acuity \<20/40, dense cataract, severe ptosis/strabismus, active ocular infection/inflammation).
* History of photosensitive epilepsy or seizure disorder triggered by visual stimuli.
* Severe motion sickness/cybersickness or inability to tolerate the AR headset.
* Significant cognitive impairment or psychiatric condition precluding informed consent or protocol compliance.
* Pregnant or breastfeeding (per investigator judgment and IRB policy).
* Any other condition that, in the investigator's opinion, would make participation unsafe or confound study results.

Where it's running

• Kaohsiung Chang Gung Memorial Hospital
  Kaohsiung, Taiwan, Taiwan Recruiting

Study contacts

• Study coordinator: Ching-Nung Wu, MD, PhD
• Email: taytay@cgmh.org.tw
• Phone: +886975369260

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.