Nutritional support for patients on dialysis using indirect calorimetry
Intra Dialytic Parenteral Nutrition During Intermittent Hemodialysis Can Close the Nutritional Gap Identified by Indirect Calorimetry: a Pilot and Feasibility Study
This study is testing if personalized nutritional support during dialysis can help improve the health of patients with chronic kidney disease who are not getting enough protein and calories.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitair Ziekenhuis Brussel Academic / other |
| Locations | 1 site (Jette, Brussel) |
| Trial ID | NCT05568914 on ClinicalTrials.gov |
What this trial studies
This study focuses on patients with chronic kidney disease undergoing intermittent hemodialysis, particularly those suffering from Protein-Energy Wasting (PEW). It aims to improve nutritional support by utilizing indirect calorimetry to accurately assess individual caloric needs, which is often not captured by standard predicting formulas. The intervention includes intradialytic parenteral nutrition (IDPN) to help close the nutritional gap identified through these assessments. By addressing the specific protein and caloric requirements of these patients, the study seeks to enhance their physical condition and overall health outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults on intermittent hemodialysis who exhibit signs of Protein-Energy Wasting.
Not a fit: Patients who are pregnant or have metabolic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the nutritional status and quality of life for patients undergoing dialysis.
How similar studies have performed: Other studies have shown promising results with similar nutritional interventions in dialysis patients, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient on intermittent hemodialysis * Protein-Energy Wasting defined as 5% within 3 months or 10% within 6 months (not due to water loss, established at the discretion of the treating physician) Exclusion Criteria: * Pregnancy * Contra-indications for the use of indirect calorimetry as stated by the AARC (oxygen therapy for COPD,...) * Metabolic diseases
Where this trial is running
Jette, Brussel
- Universitair Ziekenhuis Brussel — Jette, Brussel, Belgium (Recruiting)
Study contacts
- Principal investigator: Elisabeth De Waele, MD, PhD — Universitair Ziekenhuis Brussel
- Study coordinator: Elisabeth De Waele, MD, PhD
- Email: elisabeth.dewaele@uzbrussel.be
- Phone: +3224763354
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.