Nutritional and exercise program for older adults in acute care

Hyperproteic Oral Supplementation with Vitamin D and Resistance Training in Older Patients Admitted to the Acute Unit (SERIA)

NA · Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal · NCT06607718

This study tests whether a special nutrition and exercise program can help older adults in the hospital who are at risk of malnutrition feel stronger and healthier before they go home.

Quick facts

PhaseNA
Study typeInterventional
Enrollment105 (estimated)
Ages65 Years and up
SexAll
SponsorFundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal (other)
Locations1 site (Madrid)
Trial IDNCT06607718 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effects of nutritional and exercise interventions on older adults admitted to an acute care unit who are at risk of malnutrition or are malnourished. Participants are randomly assigned to one of four groups: resistance training, oral nutritional supplementation, a combination of both, or a control group. The study measures changes in nutritional status, body composition, strength, and physical performance at discharge and three months later. Assessments are conducted at admission, discharge, and follow-up to determine the effectiveness of the interventions.

Who should consider this trial

Good fit: Ideal candidates are older adults admitted to the acute care unit who are at risk of malnutrition or are malnourished.

Not a fit: Patients with advanced dementia, those requiring palliative care, or those with conditions contraindicating exercise will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the nutritional status and physical performance of older adults, reducing the prevalence of sarcopenia.

How similar studies have performed: Other studies have shown promising results with similar nutritional and exercise interventions in older adults, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients admitted to the Unidad de Agudos (Geriatric Acute Care) del Servicio de Geriatría at HU Ramón y Cajal who are at risk of malnutrition or malnutrition (defined with a MNA-SF score ≤ 11) and who sign the informed consent form.

Exclusion Criteria:

* patients with estimated discharge within 72 hours.
* Re-admissions (defined as previous admission in the Geriatric Acute Care in the last 3 months)
* Patients taking ONS for more than two weeks.at the time of admission.
* Patients suffering any illness or condition that prevents or contraindicates resistance physical exercise. and oral food intake.
* Food allergies or intolerances that contraindicate the SNO.
* Patients with advanced dementia (GDS stage 7) or palliative care.

Where this trial is running

Madrid

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Malnutrition, Protein, Older, Sarcopenia, Oral Nutritional Supplementation, Resistance trainning, Older adults, Acute Care

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.