Nursing intervention for weight and metabolic management in first-episode psychosis

Efficacy Study on Nursing Consultation in Weight and Metabolic Syndrome Management Based on the Carbohydrate-insulin Theory in Individuals with First-episode Psychosis (MetaKOP)

Not applicable Interventional Hospital de Basurto · NCT06650943

This study tests if a special nursing program that focuses on diet and exercise can help people with first-episode psychosis lose weight and improve their overall health compared to regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment88 (estimated)
SexAll
SponsorHospital de Basurto Academic / other
Locations1 site (Bilbao, Vizcaya)
Trial IDNCT06650943 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a nursing intervention based on the carbohydrate-insulin model to reduce weight and manage metabolic syndrome in individuals experiencing first-episode psychosis. Participants will receive specialized nursing consultations focused on dietary habits and physical activity over a series of 8 sessions. The study aims to determine if this intervention leads to significant weight loss and improvements in metabolic parameters, psychological state, and quality of life compared to routine care. Assessments will be conducted at the start, 6 months, and 12 months to measure outcomes.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with first-episode psychosis within the last 5 years who are admitted to the Early Intervention Program.

Not a fit: Patients with cognitive impairments, neurological pathologies, or those on hypoglycemic medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve weight management and reduce metabolic syndrome risk in patients with first-episode psychosis.

How similar studies have performed: Other studies have shown promising results with nursing interventions in managing metabolic syndrome, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients admitted to the Early Intervention Program (EIP).
2. First-episode psychosis (FEP) within the last 5 years.
3. Diagnosis of psychosis from the F2 spectrum or an affective disorder with psychotic symptoms according to ICD-10.

Exclusion Criteria:

1. Cognitive inability to learn or comorbid intellectual disability that interferes with study procedures.
2. Comorbid diagnosis of neurological pathology.
3. Language or comprehension impairments preventing accurate data collection.
4. Use of hypoglycemic medication before or during the study.
5. Refusal to participate

Where this trial is running

Bilbao, Vizcaya

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions First Episode PsychosisMetabolic Syndrome XFEPpsychosismetabolic syndromenursingmental health nurse
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.