Nurse practitioner-led program to help hospitalized smokers quit

Implementing Effective Smoking Cessation Pharmacotherapy for Hospitalized Smokers With Cardiopulmonary Disease

Phase 2 Interventional Baystate Medical Center · NCT05733767

This study tests a program led by nurse practitioners to help hospitalized smokers with heart and lung issues quit smoking by using better medications and support.

Quick facts

PhasePhase 2
Study typeInterventional
Enrollment424 (estimated)
Ages18 Years and up
SexAll
SponsorBaystate Medical Center Academic / other
Locations1 site (Springfield, Massachusetts)
Trial IDNCT05733767 on ClinicalTrials.gov

What this trial studies

This study evaluates a nurse practitioner-led tobacco treatment team aimed at improving smoking cessation pharmacotherapy among hospitalized patients with cardiopulmonary conditions. Patients admitted to Baystate Medical Center who smoke will be screened and randomized into either enhanced usual care or the intervention group. The primary goal is to increase the use of guideline-concordant smoking cessation medications and improve smoking cessation rates at six months post-discharge. The study will recruit 424 patients to assess the effectiveness of this intervention.

Who should consider this trial

Good fit: Ideal candidates are hospitalized patients at Baystate Medical Center with a diagnosis of a cardiopulmonary condition who smoke cigarettes.

Not a fit: Patients who are pregnant, nursing, have suicidal ideation, or are expected to have a short life expectancy will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly increase smoking cessation rates among hospitalized patients, leading to improved health outcomes.

How similar studies have performed: Other studies have shown success with similar interventions aimed at smoking cessation in hospitalized patients, indicating a promising approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Admitted to Baystate Medical Center in Springfield, MA with a cardiac or pulmonary disease diagnosis will be eligible to participate in this trial.
* Patients who smoke cigarettes
* Speak English

We will include any patients with the following diagnoses or procedures from Baystate Medical Center in Springfield, MA:

* myocardial infarction
* coronary artery bypass grafting surgery
* heart valve surgery
* percutaneous coronary intervention (PCI)
* acute coronary syndrome
* heart failure
* chronic obstructive pulmonary disease (COPD)
* asthma exacerbation.

Exclusion Criteria:

* We will exclude pregnant or nursing women, patients with current suicidal ideation, planned discharge to hospice or expected survival \<6 months, or concurrent use of daily smoked marijuana, because this can increase exhaled carbon monoxide levels, which would confound biochemical confirmation.

Where this trial is running

Springfield, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiopulmonary DiseaseSmoking CessationInpatient
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.