Noninvasive tool for diagnosing Peripheral Arterial Disease
Ultrasound Perfusion Estimation for Assessment of PAD
This study is testing a new ultrasound tool to see if it can help diagnose Peripheral Arterial Disease earlier and track how well treatments are working for people with the condition.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06952543 on ClinicalTrials.gov |
What this trial studies
This study aims to develop a new noninvasive ultrasound imaging tool for the early diagnosis of Peripheral Arterial Disease (PAD). It will also monitor disease progression and response to treatment in patients diagnosed with PAD. The study will involve both patient volunteers with symptoms of claudication and healthy volunteers for comparison. Participants will undergo ultrasound imaging to assess blood flow and perfusion in the affected areas.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with symptoms of claudication and suspected PAD, as well as healthy volunteers aged 18-75 with no significant health issues.
Not a fit: Patients with gangrene, recent surgeries, or other serious leg conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this tool could lead to earlier diagnosis and better management of Peripheral Arterial Disease, improving patient outcomes.
How similar studies have performed: Other studies have shown promise in using ultrasound imaging for vascular assessments, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Patient volunteers: * Male and Female, ages 18 years old and up * Symptom of claudication and suspected for PAD * Scheduled for vascular testing. Healthy volunteers: * Male and female, ages 18-75 years old and up * Normal BMI * No history of smoking, cardiovascular disease, or diabetes. Exclusion Criteria: Patient volunteers: * Patients with gangrene * Patients having surgery or stent * Patients with ulcer on their leg * Any health condition that does not allow proper use of ultrasound scanning * People considered in "vulnerable" populations. Healthy volunteers: * Include volunteers with BMI not more than 30 * No history of smoking * No history of (diabetes, hypertension, cardiovascular diseases) * People considered in "vulnerable" populations.
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Azra Alizad — Mayo Clinic
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.