Non-linear vs linear strength training for adults with type 2 diabetes
Official title: A Comparison of the Effects of Different Periodization-Based Strength Training Programs in Individuals With Type 2 Diabetes Mellitus
Run by Baskent University · NCT07659925 · Data updated 2026-11-12
This study tests whether non-linear or linear periodization strength training, compared with usual care, improves fitness and health markers in adults with type 2 diabetes over 8 weeks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Baskent University Academic / other |
| Locations | 1 site (Ankara, Ankara) |
| Status | Recruiting |
| Started | May 1, 2026 |
| Main results expected | November 2026 |
| Study ends | December 2026 |
| Registry record updated | June 22, 2026 |
| Trial ID | NCT07659925 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 with diagnosed type 2 diabetes who have not recently engaged in a structured exercise program and meet safety criteria.
✕Probably not a fit
Patients with significant diabetic complications or cardiovascular or respiratory conditions may receive little or no benefit and face higher risk.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this randomized trial, adults with type 2 diabetes are assigned to non-linear periodization strength training, linear periodization strength training, or usual care for 8 weeks, three sessions per week. The study will measure exercise capacity, muscle strength, body composition, quality of life, and metabolic parameters before and after the program. The goal is to determine which periodization approach, if any, provides the greatest benefits for physical function and metabolic health in this population. Safety criteria exclude individuals with advanced diabetic complications and certain cardiovascular or respiratory conditions. Baskent University Hospital serves as the study site, with Baskent University as the lead sponsor.
Why it matters
Potential benefit: If effective, the training approaches could improve strength and exercise capacity and support better metabolic control for people with type 2 diabetes.
How similar studies have gone: Prior research suggests exercise-based programs can improve strength and function in type 2 diabetes, but direct comparisons of periodization strategies are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged between 18 to 65 years * Diagnosis of Type 2 Diabetes Mellitus (T2DM) * Not having participated in any structured exercise program within the last 6 months * Willingness to participate in the study and provide written informed consent Exclusion Criteria: * Presence of nephropathy, retinopathy, or peripheral neuropathy * Presence of neurological, cognitive, or orthopedic disorders that may affect outcome measurements * Severe respiratory disease (Forced Expiratory Volume in the first second \[FEV1\] \<35% or Forced Vital Capacity \[FVC\] \<50%) * Presence of ischemic heart disease or peripheral arterial disease * History of any cardiovascular event within the last 6 months * Current malignancy
Where it's running
-
Baskent University Hospital
Ankara, Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Neslihan Duruturk, PhD — Baskent University
- Study coordinator: Ayşegül Erkoç, PT
- Email: erkcaysegl@gmail.com
- Phone: +90 553-301-36-73
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Acute Blood Flow Restriction Walking in Type 2 Diabetes
This study tests whether adding blood flow restriction to treadmill walking affects immune cells in adults with type 2 diabetes.
-
Continuous Glucose Monitoring in Type 2 Diabetes Not on Insulin
This study tests whether using a continuous glucose monitoring system helps people with type 2 diabetes who aren’t using insulin to improve blood sugar control and quality of life.
-
Differentiating heart disease in autoimmune vs. type 2 diabetes
This study tests whether adult-onset autoimmune diabetes (AID/LADA) and type 2 diabetes (T2D) differ in how diabetic heart disease develops, using advanced heart imaging in people with AID, T2D, and healthy controls.
-
Lifestyle Metabotype Study B: Understanding Personalized Glucose Responses
This study tests how lifestyle, metabolism, and brain energy use relate to each person’s blood sugar response after meals, across people with and without prediabetes or type 2 diabetes.
-
Lifestyle Metabotype Study: How Daily Habits Shape Blood Sugar
This observational study tests whether personal lifestyle and biological factors can predict how a person’s blood sugar responds after meals.
-
Switching to Zenagamtide From Tirzepatide in Adults With Overweight or Obesity With or Without Type 2 Diabetes
This study tests whether adults who are overweight or have obesity (with or without type 2 diabetes) can switch from tirzepatide to a new treatment called zenagamtide to find a tolerable dose.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.