NOA HYDRATION facial gel: see if it can improve skin smoothness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase 3 trial compares NOA HYDRATION injections to a no-treatment control to see if the gel improves facial skin smoothness in adults. Participants are randomized with a 2:1 ratio favoring the treatment group and receive intradermal injections to the face (excluding the forehead). Approximately 150 adults across seven sites in China will be enrolled and followed to assess safety and effectiveness. Inclusion focuses on adults seeking better skin quality with moderate to severe cheek laxity and dissatisfaction with appearance, while several medical exclusions ensure safety. The study aims to provide evidence on whether this investigational device can meaningfully improve facial skin attributes related to aging.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Seeking improvement of skin quality including attributes such as skin smoothness
* Has a symmetric ACSS score of Moderate (2) or Severe (3) on both cheeks
* FACE-Q Satisfaction with Skin Questionnaire sum of raw scores \<= 39 and scores of "Very Dissatisfied" or "Somewhat Dissatisfied" on the following questions:

  * How hydrated your facial skin looks?
  * How radiant your facial skin looks?

Exclusion Criteria:

* History of anaphylaxis or allergy to lidocaine, HA products, or bacterial proteins
* Active cutaneous inflammatory or infectious processes on the treatment area
* Active autoimmune disease or uncontrolled systemic disease
* Temporary soft tissue filler injections in the treatment area within 12 months
* Semi-permanent fillers anywhere in the treatment area within 36 months

Where it's running

• Beijing Hospital /ID# 281119
  Beijing, Beijing Municipality, China Recruiting
• Peking Union Medical College Hospital (West) - Xidan Campus /ID# 280945
  Beijing, Beijing Municipality, China Recruiting
• Nanjing Drum Tower Hospital /ID# 281047
  Nanjing, Jiangsu, China Recruiting
• Zhejiang Provincial People's Hospital /ID# 281041
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Abbvie Call Center
• Email: abbvieclinicaltrials@abbvie.com
• Phone: 844-663-3742

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.