NIRS and BIS monitoring during cerebral aneurysm coiling under anesthesia
Official title: Evaluation of Near-Infrared Spectroscopy and Bispectral Index Monitoring During Cerebral Aneurysm Coil Embolization
Run by Dokuz Eylul University · NCT07438275 · Data updated 2026-11-12
This study tests whether continuous NIRS and BIS monitoring during endovascular aneurysm coiling under general anesthesia can help identify cerebral desaturation and its relationship to anesthetic depth and blood flow.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 75 (estimated) |
| Sponsor | Dokuz Eylul University Academic / other |
| Locations | 1 site (Gaziantep) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | November 1, 2026 |
| Study ends | December 2026 |
| Registry record updated | October 21, 2026 |
| Trial ID | NCT07438275 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) with intracranial aneurysms scheduled for endovascular coil embolization under general anesthesia, ASA I–III, able to consent.
✕Probably not a fit
Patients with contraindications to NIRS/BIS or emergency procedures may not benefit from the monitoring approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study will monitor adults undergoing endovascular coil embolization for cerebral aneurysms with near-infrared spectroscopy (NIRS) and bispectral index (BIS) alongside standard anesthesia monitoring. Baseline rSO₂ and BIS will be recorded before induction, with ongoing measurements during the procedure to identify cerebral desaturation (defined as a ≥20% drop in rSO₂). The study will analyze associations between NIRS readings, BIS values, and hemodynamic parameters to understand multimodal neuromonitoring in neuroendovascular procedures. No additional interventions beyond routine monitoring will be performed. The goal is to inform clinical decision-making for cerebral protection during endovascular treatment.
Why it matters
Potential benefit: If successful, this approach could improve detection of cerebral desaturation and guide intraoperative management to reduce ischemic risk.
How similar studies have gone: Previous studies have used NIRS and BIS separately in neurosurgical settings; combined multimodal monitoring in this exact context is promising but not yet established.
Who can join: the full rules
Show full inclusion / exclusion criteria
* Age ≥18 years * Patients scheduled for endovascular coil embolization for intracranial (cerebral) aneurysm * American Society of Anesthesiologists (ASA) physical status I-III * Undergoing the procedure under general anesthesia * Ability to provide written informed consent Criteria Exclusion Criteria: * Refusal or inability to provide informed consent * History of severe cerebrovascular disease other than the target aneurysm * Severe cardiac, pulmonary, hepatic, or renal dysfunction * Pre-existing neurological deficits interfering with NIRS or BIS interpretation * Known scalp or skin conditions preventing proper placement of NIRS or BIS sensors * Emergency procedures * Pregnancy -
Where it's running
-
Gülay Akıncı
Gaziantep, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Gülay Akıncı, MD
- Email: dr.gulayakinci@gmail.com
- Phone: 5053851909
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.