New ultrasound technology for monitoring brain blood flow in sick newborns

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate a new ultrasound technology called NeoDoppler, which allows for continuous monitoring of cerebral blood flow in sick neonates and pre-term infants. The study will include various patient groups, including healthy preterm and term neonates, as well as those with specific medical conditions such as patent ductus arteriosus, perinatal asphyxia, and stroke. The goal is to map normal cerebral blood flow and understand how different medical conditions and procedures affect cerebral hemodynamics. The technology has been CE-certified and will be tested with the latest approved software.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Open fontanelle
* Healthy preterm or term born neonates
* Neonates with a medical condition of interest according to the different cohort studies: patent ductus arteriosus, perinatal asphyxia, stroke, pulmonary hypertension, congenital heart condition or infection/sepsis/meningitis
* Neonates in need of procedures

Exclusion Criteria:

* Caregivers not understanding/speaking Norwegian or English
* Caregivers not giving their consent

Where it's running

• Children's clinic, St. Olavs University Hospital
  Trondheim, Norway Recruiting

Study contacts

• Principal investigator: Siri Ann Nyrnes, MD, PhD — Childrens Clinic, St. Olavs University Hospital and NTNU
• Study coordinator: Siri Ann Nyrnes, MD, PhD
• Email: siri.a.nyrnes@ntnu.no
• Phone: 004793062121

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.