New treatment approach for complicated appendicitis in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates a fast track therapeutic model for pediatric patients undergoing laparoscopic appendectomy for complicated appendicitis. The study focuses on reducing postoperative complications, specifically abdominal abscesses, by implementing a new protocol for antibiotic management and discharge criteria. Patients will receive intravenous amoxicillin-clavulanic acid during hospitalization, followed by oral treatment, aiming to shorten hospital stays without increasing complication rates. The trial is based on previous studies that have shown promising results in similar therapeutic approaches.

Why it matters

Who can join: the full rules

Inclusion criteria:

* Ages 2 to 17 years. Intraoperative diagnosis of complicated appendicitis. Laparoscopic appendectomy. Agreement to participate in the study with signed informed consent.

Exclusion criteria:

* Patients requiring admission to the ICU with vasoactive support. Catarrhal or phlegmonous appendicitis. History of cystic fibrosis, Crohn's disease, or transplant that may interfere with the usual postoperative course of laparoscopic appendectomy. Contraindication to the administration of amoxicillin-clavulanic acid. Refusal to participate in the study by parents/legal guardians.

Where it's running

• Hospital de la Santa Creu i Sant Pau
  Barcelona, Barcelona, Spain Recruiting
• Hospital Germans Trias i Pujol
  Badalona, Spain Recruiting
• Hospital del Mar
  Barcelona, Spain Recruiting
• Hospital Sant Joan de Deu
  Esplugues de Llobregat, Spain Recruiting
• Hospital Universitario Dr. Josep Trueta
  Girona, Spain Recruiting
• Complejo Universitario Hospitalario de Santiago de Compostela
  Santiago de Compostela, Spain Recruiting

Study contacts

• Study coordinator: Maria Jose Martinez-Zapata, MD, PhD
• Email: mmartinezz@santpau.cat
• Phone: +34935537901

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pre-incisional ropivacaine plus Diprospan for pain after laparoscopic surgery

  This study tests whether injecting ropivacaine with Diprospan before surgery reduces pain after laparoscopic gallbladder, appendix, or hernia operations compared with ropivacaine alone.

  Recruiting Beijing Tiantan Hospital · Beijing, Beijing Municipality · NCT07626463

• Oral Lactulose to Help GI Recovery After Complicated Appendicitis

  This trial tests whether giving lactulose by mouth after appendectomy helps people recover bowel function faster than a placebo.

  Recruiting Nanchong Central Hospital · Sichuan · NCT07589465

• Laparoscopic Antibiotic Lavage to Help Prevent Abscess After Complicated Appendicitis

  This trial tests whether washing the abdomen with antibiotics during laparoscopic appendectomy can reduce the chance of an intra-abdominal abscess in people with complicated appendicitis.

  Recruiting at 10 sites Phase 3 Spaarne Gasthuis · Heerlen, Limburg and 10 other locations · NCT06841003

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.