New cardiac MRI technique using a specialized coil

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop and test a cardiac-specific coil for Fast Field-Cycling MRI, a novel imaging technique that rapidly switches field strengths to provide detailed information about heart tissue. Researchers at the University of Aberdeen will create this coil and establish normal T1 dispersion curves for healthy hearts, while also distinguishing characteristics of scar tissue in patients who have experienced a myocardial infarction. The study will involve both healthy volunteers and patients with a history of heart attacks to assess the effectiveness of this new imaging approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participant who is willing and able to give informed consent for participation in the study
* Healthy volunteers willing to give informed consent for participation in the study
* Patients diagnosed with a previous myocardial infarction

Exclusion Criteria:

* Unwillingness to participate
* Claustrophobia
* Contraindication to MRI scanning such as implantable cardiac devices
* Participants who have had a previous myocardial infarction in the past of which they may not be aware and this is discovered whilst being scanned on the 3T MRI scanner, or who may have any other cardiology condition that they were previously unaware will not be included in the healthy control group, even if they present themselves to us as "healthy" at the time of the study visit
* Pregnancy
* Body habitus that may preclude comfortable positioning of the volunteer in either of the MRI scanners (\>50cm in diameter)
* Participants with abnormal kidney function that will preclude them from receiving a contrast agent

Where it's running

• Cardiovascular Research Facility
  Aberdeen, Aberdeenshire, United Kingdom Recruiting
• University of Aberdeen and NHS Grampian
  Aberdeen, Aberdeenshire, United Kingdom Recruiting

Study contacts

• Principal investigator: Dana Dawson, DPhil — University of Aberdeen
• Study coordinator: James Ross, PhD
• Email: james.ross@abdn.ac.uk
• Phone: 01224437832

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.