Clinical trial Recruiting at 1 site Interventional Ages 18 to 35 Women only

Neurodynamic Stretch vs Myofascial Pain Release for PCOS-Related Dysmenorrhea

Official title: Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Dysmenorrhea, Quality Of Sleep And Stress In Polycystic Ovarian Syndrome.

Run by Riphah International University · NCT07645014 · Data updated 2026-11-12

This trial tests whether neurodynamic stretching with diaphragmatic breathing or myofascial pain release can help reduce cramps and improve sleep in young women with PCOS.

More Polycystic Ovary Syndrome trials

Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexWomen only
Enrollment38 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedOctober 1, 2025
Main results expectedJuly 1, 2026
Study endsJuly 1, 2026
Registry record updatedJune 12, 2026
Trial IDNCT07645014 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Women aged 18-35 with PCOS, dysmenorrhea, irregular periods, and BMI data available, not meeting exclusion criteria.

Probably not a fit

Individuals with other endocrine disorders, endometriosis, recent major surgery, or unmarried status as per exclusion criteria may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This non-blinded randomized trial compares two physical therapy approaches for young women with PCOS. Participants (n=38) will be assigned to either neurodynamic stretches with diaphragmatic breathing or to myofascial pain release therapy, using a sealed-envelope randomization. The study will evaluate changes in dysmenorrhea intensity and duration, sleep quality, and functional mobility over a 10-month period at Shaikh Zayed Hospital with non-probability convenience sampling. Group A receives abdominal, calf, and hamstring neurodynamic stretches; Group B receives myofascial pain release techniques. Outcome measures focus on symptom relief, daily function, and quality of life related to PCOS.

Why it matters

Potential benefit: If successful, participants may experience reduced menstrual pain and better sleep, potentially improving daily functioning.

How similar studies have gone: Prior studies have explored physical therapy approaches for dysmenorrhea, with mixed results; this study applies a direct comparison to determine relative effects in PCOS.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Age 18-35 years

  * Diagnosed cases of PCOS
  * Irregular periods until 3 months.
  * Presence of dysmenorrhea (Check WaLIDD Questionnaire)
  * BMI
  * Age of Menarche (13 years)

Exclusion Criteria:

* • History of endocrine disorders

  * Endometriosis
  * Tumour
  * Any major surgeries
  * Marital Status (un married)

Where it's running

  • Shaikh Zayed Hospital
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.