Neurodynamic Stretch vs Myofascial Pain Release for PCOS-Related Dysmenorrhea
Official title: Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Dysmenorrhea, Quality Of Sleep And Stress In Polycystic Ovarian Syndrome.
Run by Riphah International University · NCT07645014 · Data updated 2026-11-12
This trial tests whether neurodynamic stretching with diaphragmatic breathing or myofascial pain release can help reduce cramps and improve sleep in young women with PCOS.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 35 Years |
| Sex | Women only |
| Enrollment | 38 (estimated) |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | October 1, 2025 |
| Main results expected | July 1, 2026 |
| Study ends | July 1, 2026 |
| Registry record updated | June 12, 2026 |
| Trial ID | NCT07645014 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18-35 with PCOS, dysmenorrhea, irregular periods, and BMI data available, not meeting exclusion criteria.
✕Probably not a fit
Individuals with other endocrine disorders, endometriosis, recent major surgery, or unmarried status as per exclusion criteria may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This non-blinded randomized trial compares two physical therapy approaches for young women with PCOS. Participants (n=38) will be assigned to either neurodynamic stretches with diaphragmatic breathing or to myofascial pain release therapy, using a sealed-envelope randomization. The study will evaluate changes in dysmenorrhea intensity and duration, sleep quality, and functional mobility over a 10-month period at Shaikh Zayed Hospital with non-probability convenience sampling. Group A receives abdominal, calf, and hamstring neurodynamic stretches; Group B receives myofascial pain release techniques. Outcome measures focus on symptom relief, daily function, and quality of life related to PCOS.
Why it matters
Potential benefit: If successful, participants may experience reduced menstrual pain and better sleep, potentially improving daily functioning.
How similar studies have gone: Prior studies have explored physical therapy approaches for dysmenorrhea, with mixed results; this study applies a direct comparison to determine relative effects in PCOS.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Age 18-35 years * Diagnosed cases of PCOS * Irregular periods until 3 months. * Presence of dysmenorrhea (Check WaLIDD Questionnaire) * BMI * Age of Menarche (13 years) Exclusion Criteria: * • History of endocrine disorders * Endometriosis * Tumour * Any major surgeries * Marital Status (un married)
Where it's running
-
Shaikh Zayed Hospital
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Hafiza Iqra Rubab, MSWHPT — Riphah International University
- Study coordinator: Imran Amjad, PhD
- Email: imran.amjad@riphah.edu.pk
- Phone: 03324390125
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.