Nerve surgery to treat painful amputation neuromas

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study at Leiden University Medical Center explores surgical approaches for postamputation pain due to neuromas. It focuses on two techniques, fascicular split and targeted muscle reinnervation, to see if they provide pain relief when non-surgical options have failed. Participants are adults with intractable postamputation pain and suitable for anesthesia. Outcomes include pain relief and quality of life following the procedures. The study builds on long-standing experience with neuroma treatment at the Leiden Nerve Center and reports results from real-world clinical practice.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age older than or equal to 18 years
* Intractable postamputation pain

Exclusion Criteria:

* Cognitive impairment or delirium at the time of inclusion
* Having received previous radiotherapy on the affected limb
* Patients who are unable to comprehend the informed consent form or the questionnaires used in the current study
* Unfit for general anesthesia

Where it's running

• Leiden University Medical Center
  Leiden, South Holland, Netherlands Recruiting

Study contacts

• Principal investigator: Justus L. Groen, MD, PhD — Leiden University Medical Center
• Study coordinator: Guus A.H. Tendijck, MD
• Email: g.tendijck@hotmail.com
• Phone: +316 21320645

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.