National study on treatment options for lipedema

Surgical Treatment of Lipedema in Norway - a National Multicenter Study

Not applicable Interventional Haraldsplass Deaconess Hospital · NCT05284266

This study is testing different treatment options for women with lipedema to see which ones can help reduce pain and improve daily activities.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment220 (estimated)
Ages20 Years to 65 Years
SexFemale
SponsorHaraldsplass Deaconess Hospital Academic / other
Locations1 site (Bergen)
Trial IDNCT05284266 on ClinicalTrials.gov

What this trial studies

This study investigates various treatment approaches for lipedema, a condition characterized by painful fat accumulation in women's limbs. Participants will be assigned to receive either early or late liposuction, standard conservative treatment, or conservative treatment combined with intermittent pneumatic compression. The aim is to evaluate the effectiveness of these interventions in alleviating pain and improving daily activities for women suffering from lipedema. The study addresses a significant gap in existing research by providing well-designed randomized controlled trials focused on this condition.

Who should consider this trial

Good fit: Ideal candidates are women aged 20-65 who experience significant pain from lipedema and are in stages 1-2 or localized stage 3 of the condition.

Not a fit: Patients who are pregnant, have serious comorbidities, or have previously undergone surgical treatment for lipedema may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment options and pain relief for women suffering from lipedema.

How similar studies have performed: While there is limited research on lipedema, this study aims to fill a critical gap, suggesting that similar approaches have not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* female
* age 20-65 years
* significant pain from lipedema
* lipedema stage 1-2 or localized stage 3

Exclusion Criteria:

* Non-fluency in the Norwegian language
* pregnancy
* current malignancy
* previous surgical treatment for lipedema
* smoking
* BMI \> 28
* serious comorbidities such as cardiac-, pulmonary-, renal disease
* unwillingness to wear compression garments

Where this trial is running

Bergen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions LipedemaLiposuctionConservative treatmentIntermittent pneumatic compressionLipoedemaCompression therapySelf managementDietary management
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.