National registry for heart attack patients in Armenia

Armenian National Registry of ST-elevation Myocardial Infarction,a Multicenter Prospective Observational Study With Biocollection

This study is collecting information from heart attack patients in Armenia to see how they do in the hospital and over time, without giving any treatments.

Quick facts

• Study type: Observational
• Enrollment: 2500 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Armenian Cardiologists Association (other)
• Locations: 13 sites (Vanadzor, Lori and 12 other locations)
• Trial ID: NCT06048003 on ClinicalTrials.gov

What this trial studies

This observational study aims to collect data from patients diagnosed with ST Elevation Myocardial Infarction (STEMI) across multiple hospitals in Armenia. It will assess in-hospital mortality rates, compare short and long-term cardiovascular and all-cause mortality, and evaluate adherence to professional guidelines in real-world settings. The study will enroll approximately 2500 patients over a 24-month period, with a follow-up of 12 months for each participant. No specific interventions will be administered as it focuses on observational data collection.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who are admitted to participating hospitals for STEMI within 48 hours of symptom onset.

Not a fit: Patients who have experienced a myocardial infarction within 48 hours after a percutaneous coronary intervention or coronary artery bypass grafting may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the management and outcomes of STEMI patients, potentially leading to improved treatment protocols and reduced mortality rates.

How similar studies have performed: While this study builds on existing knowledge of STEMI management, it is part of a broader effort to improve outcomes and may provide novel insights specific to the Armenian healthcare context.

Eligibility criteria

Inclusion Criteria:

1. Adult patient (≥ 18 years of age),
2. Admitted to the participating centers for a STEMI within 48 hours of symptom onset: characterized by a rise and fall of cardiac markers (troponins) together with ST elevation in at least two contagious leads or LBBB.
3. Have given signed informed consent to participate in the study.

Non-Inclusion Criteria:

1. MI occurring ≤ 48 hours after PCI or CABG
2. The patient or the legal representative refused to sign the informed consent

Exclusion Criteria:

Withdrawal of the informed consent

Where this trial is running

Vanadzor, Lori and 12 other locations

• Vanadzor Medical Center — Vanadzor, Lori, Armenia (RECRUITING)
• Gyumri Medical Center — Gyumri, Shirak, Armenia (RECRUITING)
• French-Armenian Cardiovascular Center — Goris, Syunik, Armenia (RECRUITING)
• Heratsi Hospital Complex N1 — Yerevan, Armenia (RECRUITING)
• Erebouni Medical Center — Yerevan, Armenia (RECRUITING)
• Aramyants Medical Center — Yerevan, Armenia (RECRUITING)
• Armenia Medical Center — Yerevan, Armenia (RECRUITING)
• Astghik Medical Center — Yerevan, Armenia (RECRUITING)
• Best Life Medical Center — Yerevan, Armenia (RECRUITING)
• Nork Marash Medical Center — Yerevan, Armenia (RECRUITING)
• Shengavit Medical Center — Yerevan, Armenia (RECRUITING)
• Surb Grigor Lusavorich Medical Center — Yerevan, Armenia (RECRUITING)
• Yerevan Scientific Medical Center — Yerevan, Armenia (RECRUITING)

Study contacts

• Principal investigator: Hamlet G Hayrapetyan, Prof. — Armenian Cardiologists Association
• Study coordinator: Hamlet G Hayrapetyan, Prof.

Conditions: ST Elevation Myocardial Infarction, STEMI, Myocardial infarction, acute coronary syndrome, CV mortality, biobanking