National Colorectal Cancer Cohort for screening and patient outcomes
The National Colorectal Cancer Cohort Study-Precision Medical Research in Colorectal Cancer
This study is trying to find out what increases the risk of colorectal cancer and how to better identify and manage patients who are at high risk.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 55000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Zhejiang University Academic / other |
| Locations | 5 sites (Hangzhou, Zhejiang and 4 other locations) |
| Trial ID | NCT04074538 on ClinicalTrials.gov |
What this trial studies
The NCRCC study is a large-scale, multicenter observational cohort study that includes participants from 16 hospitals and research centers across China. It aims to assess risk factors for colorectal cancer and develop risk prediction models to identify high-risk populations. Additionally, the study seeks to discover and validate new biological markers for early diagnosis and prediction of clinical outcomes, as well as to evaluate the associations of various epidemiological determinants with survivorship endpoints among colorectal cancer patients. This comprehensive approach will enhance understanding of colorectal cancer and improve patient management.
Who should consider this trial
Good fit: Ideal candidates include men and women aged 40-74 for the screening cohort and those aged 18 and older with newly diagnosed stages I-IV colorectal cancer.
Not a fit: Patients with a history of colorectal cancer or bowel resection, as well as non-Chinese speakers, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early diagnosis and personalized treatment strategies for colorectal cancer patients.
How similar studies have performed: Other studies have shown success in identifying risk factors and biomarkers for colorectal cancer, making this approach both relevant and promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women * Mentally/physically able to consent and participate * Subjects aged ≥18 years old (Colorectal Cancer Patient Cohort, CRCPC), age 40-74 years (CRC Screening Cohort, CRCSC) * Newly-diagnosed colon and rectal cancer for stages Ⅰ-Ⅳ (CRCPC) Exclusion Criteria: * A history of colorectal cancer or bowel resection * Non-Chinese speaking
Where this trial is running
Hangzhou, Zhejiang and 4 other locations
- Second Affiliated Hospital Zhejiang University College of Medicine — Hangzhou, Zhejiang, China (Recruiting)
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences — Beijing, China (Recruiting)
- West China Hospital — Chengdu, China (Recruiting)
- Sun Yat-sen University — Guangzhou, China (Recruiting)
- Shanghai Zhongshan Hospital — Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Ke-feng Ding, PhD/MD
- Email: dingkefeng@zju.edu.cn
- Phone: 86-571-87784827
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.