National Colorectal Cancer Cohort for screening and patient outcomes
Official title: The National Colorectal Cancer Cohort Study-Precision Medical Research in Colorectal Cancer
Run by Zhejiang University · NCT04074538 · Data updated 2026-11-12
This study is trying to find out what increases the risk of colorectal cancer and how to better identify and manage patients who are at high risk.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 55000 (estimated) |
| Sponsor | Zhejiang University Academic / other |
| Locations | 5 sites (Hangzhou, Zhejiang and 4 other locations) |
| Status | Recruiting |
| Started | January 1, 2013 |
| Main results expected | December 2035 |
| Study ends | December 2035 |
| Registry record updated | August 30, 2019 |
| Trial ID | NCT04074538 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include men and women aged 40-74 for the screening cohort and those aged 18 and older with newly diagnosed stages I-IV colorectal cancer.
✕Probably not a fit
Patients with a history of colorectal cancer or bowel resection, as well as non-Chinese speakers, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The NCRCC study is a large-scale, multicenter observational cohort study that includes participants from 16 hospitals and research centers across China. It aims to assess risk factors for colorectal cancer and develop risk prediction models to identify high-risk populations. Additionally, the study seeks to discover and validate new biological markers for early diagnosis and prediction of clinical outcomes, as well as to evaluate the associations of various epidemiological determinants with survivorship endpoints among colorectal cancer patients. This comprehensive approach will enhance understanding of colorectal cancer and improve patient management.
Why it matters
Potential benefit: If successful, this study could lead to improved early diagnosis and personalized treatment strategies for colorectal cancer patients.
How similar studies have gone: Other studies have shown success in identifying risk factors and biomarkers for colorectal cancer, making this approach both relevant and promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women * Mentally/physically able to consent and participate * Subjects aged ≥18 years old (Colorectal Cancer Patient Cohort, CRCPC), age 40-74 years (CRC Screening Cohort, CRCSC) * Newly-diagnosed colon and rectal cancer for stages Ⅰ-Ⅳ (CRCPC) Exclusion Criteria: * A history of colorectal cancer or bowel resection * Non-Chinese speaking
Where it's running
-
Second Affiliated Hospital Zhejiang University College of Medicine
Hangzhou, Zhejiang, China Recruiting -
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Beijing, China Recruiting -
West China Hospital
Chengdu, China Recruiting -
Sun Yat-sen University
Guangzhou, China Recruiting -
Shanghai Zhongshan Hospital
Shanghai, China Recruiting
Study contacts
- Study coordinator: Ke-feng Ding, PhD/MD
- Email: dingkefeng@zju.edu.cn
- Phone: 86-571-87784827
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.