National cohort study on liver cirrhosis in Switzerland

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study aims to follow patients with liver cirrhosis in Switzerland to collect and analyze a wide range of data, including epidemiological, clinical, histological, psychosocial, and patient-reported outcomes. The study will also biobank biological materials from participants to support future research. By systematically documenting these aspects, the study seeks to understand the disease better and identify potential therapeutic strategies to prevent the need for liver transplantation. The data collected will be used to investigate specific hypotheses related to the progression and management of cirrhosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* A) Patients with chronic liver disease and histologically proven cirrhosis
* B) Control subjects with no signs of cirrhosis

Exclusion Criteria:

* Age \<18 years
* patients who developed hepatocellular carcinoma (HCC) and/or cholangiocellular carcinoma (CCC)

Where it's running

• Gastroenterology and Hepatology, Cantonal Hospital Ticino
  Lugano, Canton Ticino, Switzerland Recruiting
• University Centre for Gastrointestinal and Liver Diseases, University Hospital Basel, Switzerland
  Basel, Switzerland Recruiting
• Gastroenterology and Hepatology, Lausanne University Hospital
  Lausanne, Switzerland Recruiting
• Department of Visceral Surgery and Medicine, University Hospital of Berne
  Bern, Switzerland Not yet recruiting
• Gastroenterology and Hepatology, University Hospital Geneva
  Geneva, Switzerland Not yet recruiting
• Ticino Liver Centre
  Lugano, Switzerland Not yet recruiting

Study contacts

• Principal investigator: Christine Bernsmeier, Prof. Dr. med. — University Centre for Gastrointestinal and Liver Diseases, University Hospital Basel, Switzerland
• Study coordinator: Christine Bernsmeier, Prof. Dr. med.
• Email: christine.bernsmeier@clarunis.ch
• Phone: +41 61 265 2525

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.