Nasal airflow to ease breathing for tracheostomized patients on ventilators

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares continuous nasal airflow, nasal sprays, and facial airflow to determine their effect on dyspnea and respiratory drive in tracheotomized patients on mechanical ventilation. It is an interventional study that assesses non-pharmacological approaches to restore nasal stimulation as a potential means to improve comfort during weaning. Participants are adults with tracheostomies, on ventilation, and reporting dyspnea, and are evaluated across baseline and three intervention conditions. The study is conducted at Hôpital Pitié-Salpêtrière in Paris under Assistance Publique - Hôpitaux de Paris.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years
2. Tracheostomy and mechanical ventilation
3. Dyspnea ≥3
4. Consent to participate
5. Affiliation to health insurance

Exclusion Criteria:

1. Agitation, delirium
2. Continuous use of sedatives
3. Patients under law protection
4. Inmates
5. Patients without health insurance
6. Breastfeeding and pregnancy

Where it's running

• Hôpital Pitié Salpêtrière
  Paris, France Recruiting

Study contacts

• Principal investigator: Martin Dres, MD PhD — Assistance Publique - Hôpitaux de Paris
• Study coordinator: Martin DRES, MD PhD
• Email: martin.dres@aphp.fr
• Phone: +33142167809

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Diffusion MRI to map nerve lesions in obstetric brachial plexus palsy

  This study tests diffusion MRI and tractography to better understand nerve injuries in people with obstetric brachial plexus palsy.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07767708

• Long-term心理 and cognitive check after stem cell transplant for immune deficiencies

  This study tests the long-term neurocognitive and psychological functioning of 6–8 year-old children who had an allogeneic stem cell transplant for a primary immune deficiency, at least two years after the transplant.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07766304

• Benchmarking AI language models against tumor boards for oncology treatment decisions

  This project tests whether frontier AI language models can match the treatment recommendations of multidisciplinary tumor boards for common cancers using standardized synthetic cases.

  Recruiting Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt and 4 other locations · NCT07739121

• Gut microbes and autoinflammatory diseases: how they may be linked

  This study tests whether gut bacteria and their byproducts relate to digestive and inflammatory symptoms in people with autoinflammatory diseases.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07718555

• How Eye Dominance Affects Fusion in Healthy Adults

  This study tests whether fusional vergence measurements differ when tested on the dominant eye versus the non-dominant eye in healthy adults.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07697131

• Breast cancer risk check for night shift workers with a personalized prevention plan

  This study tests whether a personalized prevention plan helps female night shift workers at higher risk for breast cancer stick to healthier habits and screening over 5 years.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT07630935

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.