NAD+ supplement effects on cognition in Latina women
NAD+ Oral Supplement Pilot Intervention in Adult Females
This study is testing if a daily NAD+ supplement can help improve thinking skills and lower inflammation in healthy Latina women aged 40 to 80.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | Female |
| Sponsor | University of Rhode Island Academic / other |
| Locations | 2 sites (Kingston, Rhode Island and 1 other locations) |
| Trial ID | NCT06579209 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of Nicotinamide adenine dinucleotide (NAD+) on cognitive function and biomarkers in healthy Latina women aged 40-80. Participants will take either NAD+ or a placebo daily for four weeks and undergo cognitive testing and blood draws before and after the intervention. The study aims to determine if NAD+ can improve executive function and reduce inflammatory markers associated with neurodegenerative diseases.
Who should consider this trial
Good fit: Ideal candidates are Latina women aged 40-80 with a BMI of 18.5 or above and a history of three or more adverse childhood experiences.
Not a fit: Patients who are pregnant, breastfeeding, or taking hormone medication may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to new interventions for improving cognitive health in Latina women.
How similar studies have performed: While there is ongoing research into NAD+ and cognitive health, this specific approach targeting Latina women is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Identify as Latina, have three or more adverse childhood experiences, and a BMI of 18.5 or above Exclusion Criteria: * Those who are taking hormone medication, pregnant or breastfeeding
Where this trial is running
Kingston, Rhode Island and 1 other locations
- University of Rhode Island — Kingston, Rhode Island, United States (Recruiting)
- Independence Square, University of Rhode Island — Pawtucket, Rhode Island, United States (Recruiting)
Study contacts
- Study coordinator: Cindy E Tsotsoros, PhD
- Email: cindy-tsotsoros@uri.edu
- Phone: (401) 874-7425
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.