Multimodal profiling of adults hospitalized with acute heart failure and cardiogenic shock

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project collects clinical findings, imaging results, and biomarkers—including sex-specific factors—together with additional blood and urine samples for biobanking from adults hospitalized with acute heart failure and SCAI stage B–E cardiogenic shock. No experimental treatments are given; researchers will use routinely collected care data plus the stored samples to define phenotypes and search for associations with 30‑day mortality and other outcomes. Participants will be followed after hospital discharge to capture short‑term outcomes. The aim is to improve risk stratification and understanding of distinct cardiogenic shock presentations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients hospitalized with acute heart failure SCAI stage B - E.

Exclusion Criteria:

* Not capable of providing informed consent due to reasons not attributable to cardiogenic shock
* Cardiogenic shock following cardiothoracic surgery

Where it's running

• University Heart Center Freiburg - Bad Krozingen
  Bad Krozingen, Germany Recruiting
• University Medical Center Freiburg, Interdisciplinary Medical Intensive Care
  Freiburg im Breisgau, Germany Recruiting
• Department for Internal Medicine 8, Clinic for Cardiology and Rhythmology, University Clinic of the Paracelsus Medi-cal University Nuremberg
  Nuremberg, Germany Recruiting
• Schwarzwald Baar Klinikum Villingen-Schwenningen, Klinik für Kardiologie und Intensivmedizin
  Villingen-Schwenningen, Germany Recruiting

Study contacts

• Study coordinator: Lucas Bacmeister, MD
• Email: lucas.bacmeister@uniklinik-freiburg.de
• Phone: 004976127034010

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.