MRI techniques for patients with hemifacial spasm
Clinical Research on Patients With Hemifacial Spasm by Multi-planar Reconstruction, Curved Planar Reconstruction and Magnetic Resonance Virtual Endoscopy
This study is testing new MRI techniques to see if they can better show the nerve and blood vessel issues in people with hemifacial spasm to help plan their surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 20 Years to 60 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT04645277 on ClinicalTrials.gov |
What this trial studies
This study investigates the use of advanced magnetic resonance imaging techniques, specifically curved planar reconstruction and magnetic resonance virtual endoscopy, to better visualize neurovascular compressions in patients with hemifacial spasm. Traditional imaging methods may not adequately identify the details of these compressions, particularly when the vessels involved are veins rather than arteries. By employing three-dimensional analytic techniques, the study aims to enhance the sensitivity and specificity of imaging, which could assist in planning surgical interventions. The study focuses on patients with a history of unilateral facial muscle spasms lasting at least one year.
Who should consider this trial
Good fit: Ideal candidates are patients with primary hemifacial spasm who have experienced unilateral facial muscle spasms for at least one year.
Not a fit: Patients with secondary causes of hemifacial spasm, such as tumors or cysts, or those with precarious health status may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical planning and outcomes for patients suffering from hemifacial spasm.
How similar studies have performed: While traditional imaging methods have been widely used, the novel application of advanced three-dimensional techniques in this context is relatively untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Primary HFS patients according to medical history and typical facial muscle spasms that are unilateral, involuntary, and had intermittent contractions innervated by the ipsilateral facial nerve. The patient has 1 year disease duration at least. Exclusion Criteria: * Secondary causes of HFS, such as tumors or cysts compressing the facial nerve in the cerebellar pontine cistern; Precarious general health status; Percutaneous lesions or surgical treatments; Cardiac pacemaker or metal implants.
Where this trial is running
Xi'an, Shaanxi
- The First Affiliated Hospital of Xi'an Jiaotong University — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Principal investigator: Ming Zhang, M.D. & Ph.D. — First Affiliated Hospital Xi'an Jiaotong University
- Study coordinator: Yuan Wang, M.D.
- Email: wangyuan8003@126.com
- Phone: 0086-13324598144
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.