MOVED: a web-based mood-elevating program for Veterans with PTSD
Official title: A Randomized Controlled Trial of a Web-Based Moral Elevation Intervention for Veterans With PTSD
Run by VA Office of Research and Development · NCT06788678 · Data updated 2026-11-12
This study tests MOVED, a web-based, self-guided program to see if it can reduce PTSD symptoms and improve social functioning and quality of life for Veterans compared with a neutral, supportive control.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | VA Office of Research and Development Federal |
| Locations | 1 site (Temple, Texas) |
| Status | Recruiting |
| Started | August 10, 2026 |
| Main results expected | June 30, 2029 |
| Study ends | September 30, 2029 |
| Registry record updated | August 19, 2026 |
| Trial ID | NCT06788678 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Veterans with a current PTSD diagnosis (CAPS-5) who are English-speaking, have internet access, are enrolled in VISN 17, and are not currently receiving trauma-focused therapy or meeting exclusion criteria.
✕Probably not a fit
Patients with severe traumatic brain injury, active psychosis or mania, current suicide risk, or those undergoing active trauma-focused treatment may not benefit from MOVED.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial evaluates MOVED, a self-guided web-based intervention designed to elicit moral elevation in Veterans with PTSD. The study compares MOVED to a generic supportive control over 4 weeks (8 sessions) to see if it reduces PTSD symptoms and improves social functioning and quality of life. Participants must have PTSD, be English-speaking, and have internet access, with enrollment limited to those in the VISN 17 system and without certain comorbid conditions or ongoing trauma-focused therapies. The primary care setting is a VA health system site in Temple, Texas, targeting feasible, scalable, stand-alone treatment options. Outcomes include PTSD symptom change and broader psychosocial functioning.
Why it matters
Potential benefit: If successful, MOVED could offer an accessible, stand-alone option to help Veterans with PTSD improve symptoms, social functioning, and quality of life.
How similar studies have gone: Prior pilot work in Veterans suggested the MOVED approach is feasible and acceptable, supporting further testing in a larger randomized trial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Enrolled in a VISN 17 health care system * English-speaking and able to provide written informed consent * Willingness to complete study procedures and be randomized * Internet access and an electronic device to complete the web-based sessions * Current diagnosis of PTSD based on the CAPS-5 * History of PTSD diagnosis for at least 1 year Exclusion Criteria: * History of severe traumatic brain injury indicated by medical record review and the Ohio State Traumatic Brain Injury Identification Method (OSU TBI-ID) * Current psychosis or mania as indicated by medical record review and the Mini International Neuropsychiatric Interview (MINI) * Current suicide risk based on the Beck Depression Inventory-II (BDI-II) * Currently enrolled and actively participating in a trauma-focused treatment including: * Cognitive Processing Therapy * Prolonged Exposure * Eye Movement Desensitization Reprocessing
Where it's running
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Central Texas Veterans Health Care System, Temple, TX
Temple, Texas, United States Recruiting
Study contacts
- Principal investigator: Adam P. McGuire, PhD — Central Texas Veterans Health Care System, Temple, TX
- Study coordinator: Adam P McGuire, PhD
- Email: Adam.McGuire@va.gov
- Phone: (254) 297-5173
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.