Monthly digital financial hardship screening for people with advanced cancer
Longitudinal Screening for Financial Hardship to Improve Outcomes in Patients With Advanced Cancer
This project tests whether monthly remote digital financial hardship screening helps adults with advanced or metastatic cancer who are receiving non-curative systemic therapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1000 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Alliance Foundation Trials, LLC. Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 7 sites (Phoenix, Arizona and 6 other locations) |
| Trial ID | NCT06963723 on ClinicalTrials.gov |
What this trial studies
Adults with advanced or metastatic cancer receiving outpatient systemic therapy with non-curative intent will be enrolled and receive either monthly remote digital financial hardship screening with connections to financial navigation resources or enhanced usual care. The digital screening is delivered monthly to identify financial distress and trigger referrals to financial navigation and support. Primary patient-centered outcomes include financial worry, health-related quality of life, symptom burden, and patient-reported treatment adherence, with exploratory outcomes including overall survival, patient-reported economic burden, support received, coping strategies, and insurance literacy. The intervention builds on preliminary data suggesting screening can improve links to assistance and seeks to determine whether repeated remote screening leads to better patient-centered outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults (age ≥21) with advanced or metastatic cancer who speak English or Spanish, have been on systemic non-curative therapy for at least two months, have an expected life expectancy of at least six months, and can provide informed consent.
Not a fit: Patients receiving therapy with curative intent, not on systemic non-curative treatment, with life expectancy under six months, with cognitive deficits preventing consent, or who do not speak English or Spanish are unlikely to receive benefit from this intervention.
Why it matters
Potential benefit: If successful, the intervention could reduce financial worry, improve quality of life and treatment adherence, and help connect patients to resources that may improve overall outcomes.
How similar studies have performed: Prior studies have shown financial navigation can mitigate financial hardship and preliminary data suggest screening improves connections to assistance, but repeated remote screening as a formal intervention is still relatively untested in large trials.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Minimum age of 21 2. Understands English and/or Spanish 3. Has a diagnosis of advanced/metastatic cancer 4. Currently undergoing systemic therapy (enteral or parenteral) with non-curative intent 5. Has been receiving treatment for at least 2 months 6. Life expectancy of at least 6 months, in the opinion of the treating oncologist 7. Cognitively able to give informed consent Exclusion Criteria: 1. Under the age of 21 2. Does not understand English or Spanish 3. Has cognitive deficits that would preclude understanding of consent form and/or questionnaires 4. Undergoing treatment with curative intent (e.g., adjuvant chemotherapy for breast, lung, or ovarian cancer, primary curative therapy for testis cancer or lymphoma) 5. Not undergoing systemic therapy (enteral or parenteral) with non-curative intent 6. Receiving treatment for fewer than 2 months 7. Life expectancy is less than 6 months, in the opinion of the treating oncologist
Where this trial is running
Phoenix, Arizona and 6 other locations
- Dignity Health — Phoenix, Arizona, United States (Recruiting)
- New Hampshire Oncology-Hematology, PA — Concord, New Hampshire, United States (Recruiting)
- Solinsky Center for Cancer Care — Manchester, New Hampshire, United States (Recruiting)
- New York City Health and Hospitals — New York, New York, United States (Recruiting)
- Sanford Health — Fargo, North Dakota, United States (Recruiting)
- Gibbs Cancer Center — Spartanburg, South Carolina, United States (Recruiting)
- Pan American Center for Oncology Trials — San Juan, Puerto Rico (Recruiting)
Study contacts
- Principal investigator: Victoria Blinder, MD, MSc — Memorial Sloan Kettering Cancer Center
- Study coordinator: AFT Quality Management Group Inbox
- Email: clinicaltrials.queries@alliancefoundationtrials.org
- Phone: 617-732-8727
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.