Monitoring oxygen levels during intubation in critically ill patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the feasibility of monitoring end-tidal oxygen concentration (EtO2) during preoxygenation for intubation in critically ill patients in the intensive care unit (ICU). It involves a prospective non-comparative interventional approach where EtO2 will be measured both in the pharynx and on the facemask during the intubation procedure. The goal is to determine if this dual monitoring can provide a more accurate assessment of preoxygenation compared to traditional methods. The study will last no longer than one hour, including device setup.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Requiring an intubation in ICU for acute respiratory failure defined as a respiratory rate ≥ 25/min or clinical signs of respiratory distress or hypoxemia defined as oxygen requirement ≥ 15L/min or FiO2 ≥80% to maintain SpO2 ≥92% or a PaO2/FiO2 ratio \<100 mmHg
* With preoxygenation by noninvasive ventilation

Exclusion Criteria:

* Intubation for cardiac arrest
* EtO2 monitoring not available
* Pulsed oxygen saturation monitoring specific for the study not available
* Preoxygenation by high-flow nasal oxygen therapy or bag-mask ventilation
* Allergy to lidocaine (for local nasal anesthesia)
* Previously
* Patient not affiliated or excluded from social protection, or under law protection (namely minors, pregnant or breastfeeding women, persons deprived of their liberty by court or administrative decision)
* Previously included in the study

Where it's running

• CHR d'ORLEANS
  Orléans, France Recruiting

Study contacts

• Principal investigator: Mai-Anh NAY, PH — CHR d'Orléans
• Study coordinator: Mai-Anh NAY, PH
• Email: mai-anh.nay@chr-orleans.fr
• Phone: +33238575253

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.