Monitoring neuromuscular blockade in the ICU: a reliability look

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study evaluates the reliability of neuromuscular blockade monitoring in adults admitted to the ICU and treated with neuromuscular blocking agents. It includes assessments of measurements at the ulnar nerve with TOF stimulation and tracks safety by monitoring for adverse events such as respiratory effort or patient-ventilator asynchrony over 24-hour periods. The trial discusses how monitoring methods align with clinical context and existing guidelines, and it explores potential anomalies when neuromuscular blockade is present or absent. The study is conducted at a single center, led by Centre Hospitalier Intercommunal Aix-Pertuis, and focuses on practical monitoring in routine ICU care. Overall, it aims to determine whether current monitoring approaches provide reliable information across typical ICU scenarios.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients
* Patients admitted to the intensive care unit who have been receiving neuromuscular blocking agents for at least 24 hours during their stay - Consent obtained from the patient or emergency consent obtained from family members
* Patients covered by the French social security system, regardless of the specific plan

Exclusion Criteria:

* Patients who have already been exposed to prolonged neuromuscular blockade or who have been receiving continuous neuromuscular blockade for less than 24 hours
* Allergy to neuromuscular blocking agents
* Patients with a neurological condition that alters the interpretation of neuromuscular blockade or contraindicates the use of neuromuscular blocking agents
* Patients enrolled in an interventional study
* Patients who object to the collection of their medical data for this study
* Patients under the age of 18
* Patients deprived of their liberty, under guardianship, or under conservatorship
* Pregnant or breastfeeding women

Where it's running

• Centre Hospitalier Intercommunal Aix-Pertuis
  Aix-en-Provence, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.