Monitoring glycocalyx to predict complications after heart surgery
Evaluation de l'utilité du Monitorage du Glycacalyx Pour prédire Les Complications du Patient de Chirurgie Cardiaque
This study is trying to see if changes in a protective layer around blood vessels can help predict complications in patients after heart surgery that uses a heart-lung machine.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 77 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | University Hospital, Rouen Academic / other |
| Locations | 1 site (Rouen) |
| Trial ID | NCT06136637 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the changes in microcirculation and glycocalyx thickness during cardiac surgery involving cardiopulmonary bypass. It aims to assess how variations in glycocalyx thickness can predict major complications within the first 24 hours post-surgery. By closely monitoring these parameters, the study seeks to provide insights into patient outcomes and improve postoperative care. The study will involve patients undergoing scheduled cardiac surgeries that require cardiopulmonary bypass lasting over 60 minutes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are scheduled for cardiac surgery requiring cardiopulmonary bypass.
Not a fit: Patients not undergoing cardiac surgery or those with a planned surgery duration of less than 60 minutes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the ability to predict and manage complications after cardiac surgery, leading to improved patient outcomes.
How similar studies have performed: While the specific approach of monitoring glycocalyx in this context may be novel, similar studies have shown promise in understanding microcirculation and its impact on surgical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
* Patient of legal age (age ≥ 18 years) * Patient undergoing scheduled cardiac surgery with cardiopulmoary bypass (CPB) (expected duration of CPB \> 60 min) * Person informed with collection of non-opposition at the latest, the day before the operation - Person affiliated to a social security system
Where this trial is running
Rouen
- Rouen University Hospital — Rouen, France (Recruiting)
Study contacts
- Study coordinator: Demailly Zoé, MD
- Email: zoe.demailly@chu-rouen.fr
- Phone: 0232882440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.