Monitoring cortisol levels in different body fluids
Real-time Monitoring of Cortisol - Comparison of Cortisol Levels in Four Biological Fluids
This study is testing a new way to measure cortisol levels in sweat, saliva, interstitial fluid, and blood to see how they compare and improve monitoring for adrenal-related conditions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 12 (estimated) |
| Ages | 18 Years to 30 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire Vaudois Academic / other |
| Locations | 1 site (Lausanne, Vaud) |
| Trial ID | NCT06008184 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare cortisol levels in four biological fluids: sweat, saliva, interstitial fluid, and blood. By utilizing a non-invasive and ambulatory method, the study seeks to validate a continuous cortisol measurement device currently under development. Participants will undergo 24-hour sampling of these fluids to assess the correlation of cortisol levels across different mediums. The findings could enhance our understanding of cortisol secretion patterns and improve monitoring methods for conditions related to adrenal function.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals aged 18 to 30 with a normal BMI and stable weight.
Not a fit: Patients who are pregnant, breastfeeding, or have any medical issues or treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and non-invasive monitoring of cortisol levels for patients with adrenal disorders.
How similar studies have performed: While the approach of real-time cortisol monitoring is innovative, similar studies have not been extensively documented, indicating this may be a novel exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Healthy controls: Inclusion Criteria: * age between 18 and 30 years old * normal BMI 18 to 25 kg/m2 * weight stability Exclusion Criteria: * pregnancy, breastfeeding, irregular menses * any medical treatment * any medical issues * pilocarpine allergy, or latex allergy * glaucoma or acute irritis
Where this trial is running
Lausanne, Vaud
- Centre Hospitalier Universitaire Vaudois (CHUV) — Lausanne, Vaud, Switzerland (Recruiting)
Study contacts
- Principal investigator: Nelly Pitteloud, MD — Centre Hospitalier Universitaire Vaudois
- Study coordinator: Adelina Ameti
- Email: adelina.ameti@chuv.ch
- Phone: 0041795568630
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.