Monitoring brain activity and oxygen levels in ARDS patients in the ICU

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the feasibility of using non-invasive monitoring techniques, specifically processed electroencephalography (EEG) and near-infrared spectroscopy (NIRS), to assess the optimal depth of sedation in patients with acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU). The research aims to determine how these monitoring methods can help minimize the correlation between brain oxygenation and sedation levels. Data collected will include demographic information, medical history, and sedation dosages, allowing for a comprehensive analysis of sedation effects on cerebrovascular reactivity in ARDS patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient admitted to the ICU
* ARDS confirmed according to the Berlin Definition
* Invasive mechanical ventilation
* Deep sedation and/or neuromuscular blockade required for ARDS treatment at the discretion of the treating medical team
* Application of monitoring devices feasible

Exclusion Criteria:

* More than 24 hours elapsed since ICU admission
* Death is deemed imminent and inevitable during the next 24 hours
* Known allergy to a textile component of the device
* Consent declined from patient or authorized third party
* The treating clinician believes that participation in the study would not be in the best interest of the patient

Where it's running

• Health Sciences Centre Winnipeg
  Winnipeg, Manitoba, Canada Recruiting

Study contacts

• Principal investigator: Asher Mendelson, MD PhD — University of Manitoba
• Study coordinator: Asher Mendelson, MD PhD
• Email: asher.mendelson@umanitoba.ca
• Phone: 204-787-8059

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.