Modified trabeculectomy after failed combined phaco with GATT
Official title: Modified Trabeculectomy for Management of Early Failure of Combined Phaco With GATT or With Goinopuncture
Run by Assiut University · NCT07455786 · Data updated 2026-11-12
This trial tries a modified trabeculectomy operation to lower eye pressure in people whose cataract surgery combined with GATT or phacogoniopuncture did not control their glaucoma.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 70 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Status | Recruiting |
| Started | April 1, 2026 |
| Main results expected | April 1, 2027 |
| Study ends | April 1, 2027 |
| Registry record updated | March 6, 2026 |
| Trial ID | NCT07455786 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with glaucoma who previously had combined phacoemulsification with GATT or phacogoniopuncture and continue to have inadequate intraocular pressure control are the intended candidates.
✕Probably not a fit
People who never had phaco with GATT or phacogoniopuncture, healthy individuals without glaucoma, or patients whose glaucoma is well controlled on current therapy are unlikely to benefit from this procedure.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-site interventional protocol enrolls patients with glaucoma who previously underwent combined phacoemulsification with GATT or phacogoniopuncture and have persistent uncontrolled intraocular pressure. Participants will receive a modified trabeculectomy procedure that incorporates techniques such as deep non-penetrating sclerectomy, viscocanalostomy, and a small-incision trabeculectomy that avoids Tenon's capsule. The approach is intended to provide an alternative when ab-interno MIGS approaches have failed or are unsuitable, with postoperative follow-up to monitor intraocular pressure and complications. Outcomes will focus on pressure lowering, need for medications or further surgery, and procedure-related adverse events.
Why it matters
Potential benefit: If successful, this procedure could lower intraocular pressure for patients whose glaucoma was not controlled after phaco with GATT and reduce the need for additional medications or surgeries.
How similar studies have gone: Traditional trabeculectomy is well established for lowering eye pressure, but the specific modified small-incision, Tenon-avoiding approach after failed phaco-GATT has limited published outcome data and is less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients had combined phaco surgery with GATT. * All patients had phaco with goinopuncture. Exclusion Criteria: * Healthy patient. * No history of phaco surgery with GATT or goinopuncture.
Where it's running
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Assiut univercity
Asyut, Egypt Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.