Modified Constraint-Induced Movement Therapy vs. Mirror Therapy for hemiplegic stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with stroke and hemiplegia are randomly assigned to receive either Modified Constraint-Induced Movement Therapy or Mirror Therapy. The trial compares effects on upper-limb motor function, daily activities, and overall independence, using standard care as a baseline. It follows a prospective, randomized, single-blind design with ethical approval and informed consent. Outcomes focus on paretic limb recovery and quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \* Diagnosis: Confirmed first ischemic or hemorrhagic stroke with clinical and neurological evaluation.

  * Time Since Stroke: 3 to 24 months post-stroke onset.
  * Hemiplegia: Significant motor deficit in the affected upper extremity.
  * Motor Function Level: Presence of mild to moderate motor impairment in the affected upper extremity (FMA-UE score appropriate for the application of modified CIMT and mirror therapy).
  * Cognitive Status: Adequate cognitive capacity to understand and follow the study protocols (Mini-Mental State Examination score of 20 or above).
  * Visual Perception: Adequate visual perception to perform mirror therapy.
  * Comorbidities: Absence of severe coexisting medical conditions that prevent participation (e.g., uncontrolled cardiovascular diseases, severe psychiatric disorders).
  * Prior Treatments: No prior intensive participation in the interventions investigated in this study (modified CIMT or mirror therapy).
  * Consent: Voluntary agreement to participate and signed informed consent form.

Exclusion Criteria:

* \* Uncontrolled diabetes or other metabolic disorders.

  * Progressive non-stroke neurological diseases (e.g., Parkinson's disease, multiple sclerosis).
  * Terminal illness or short life expectancy.
  * Severe cognitive impairment preventing comprehension or execution of the study protocols (e.g., advanced dementia).
  * Severe visual impairment that prevents mirror therapy application (e.g., uncorrected visual acuity loss, neglect).
  * Severe visuospatial perception disorders making it difficult to perceive or interpret the mirror image.
  * Absence or minimal level of active movement in the affected upper extremity (limiting the applicability of modified CIMT).
  * Significant motor deficit in the unaffected upper extremity.
  * Severe and uncontrolled spasticity in the upper extremity.

Where it's running

• Akay Special Education and Rehabilitation Center
  Kastamonu, Merkez, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: NİSA KILIÇ KOÇAK, Msc Student
• Email: nisakilicas12@gmail.com
• Phone: +905455932547

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.