Modified constraint-induced movement therapy (m-CIMT) for improving upper arm use after acute ischemic stroke
Official title: Effectiveness of m-CIMT of the Upper Limb in Acute Post-stroke Patients.
Run by Hospital Clinic of Barcelona · NCT07233161 · Data updated 2026-11-12
This will try m-CIMT—restraining the unaffected arm and doing daily targeted exercises—to see if hospitalized adults within 15 days of an ischemic stroke regain better use of their affected arm.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 66 (estimated) |
| Sponsor | Hospital Clinic of Barcelona Academic / other |
| Locations | 1 site (Barcelona, Barcelona) |
| Status | Recruiting |
| Started | April 23, 2025 |
| Main results expected | December 20, 2026 |
| Study ends | December 20, 2026 |
| Registry record updated | November 18, 2025 |
| Trial ID | NCT07233161 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults hospitalized within the first 15 days after an ischemic stroke who have a motor deficit in one upper limb, can follow simple instructions, and can provide informed consent are ideal candidates.
✕Probably not a fit
Patients with unstable clinical conditions, bilateral upper limb strokes, prior disabling upper limb injuries, severe behavioral disturbance, or inability to follow instructions are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The intervention delivers modified constraint-induced movement therapy over seven consecutive days in hospitalized patients within 15 days of an ischemic stroke. Each day participants wear a restraint on the unaffected upper limb for three hours and receive one focused physiotherapy session for the affected arm. The program emphasizes intensive, task-specific practice to increase use and functional recovery of the paretic limb. Patients with unstable medical conditions, prior bilateral upper limb strokes, or musculoskeletal injuries that limit the affected limb are excluded.
Why it matters
Potential benefit: If successful, patients could experience faster and greater recovery of arm function during the early post-stroke period.
How similar studies have gone: Constraint-induced movement therapies have shown benefit in subacute and chronic stroke populations, but evidence specifically in the very early acute phase is limited though promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ischaemic stroke. * Hospitalised patient (first 15 days). * Ability to understand and execute simple instructions. * Over 18 years of age. * Upper limb motor deficit. * Sign the informed consent document. Exclusion Criteria: * Unstable clinical/medical condition. * Limitation of the upper limb due to a previous stroke. * Strokes affecting both upper limbs bilaterally. * Fractures/dislocations in the joints of the affected upper limb that may affect recovery. * Severe behavioural disturbance.
Where it's running
-
Hospital Clinic de Barcelona
Barcelona, Barcelona, Spain Recruiting
Study contacts
- Study coordinator: Maria S Suarez, Fisioterapia
- Email: suarezi@clinic.cat
- Phone: +34689409432
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.