Model for predicting causes of chest pain
Official title: A Prospective Study of Acute Nontraumatic Chest Pain - Warning and Classification
Run by Beijing Anzhen Hospital · NCT06196307 · Data updated 2026-11-12
This study is trying to create a tool that helps doctors better understand the causes of chest pain in patients so they can provide the right treatment more quickly.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Beijing Anzhen Hospital Academic / other |
| Locations | 1 site (Beijing, Chaoyang) |
| Status | Recruiting |
| Started | August 30, 2022 |
| Main results expected | December 30, 2027 |
| Study ends | December 30, 2028 |
| Registry record updated | February 5, 2026 |
| Trial ID | NCT06196307 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who have experienced acute non-traumatic chest pain and are willing to provide informed consent.
✕Probably not a fit
Patients with traumatic chest pain or those with systemic pain from malignant tumors or rheumatic diseases will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to develop an early warning and classification model for acute non-traumatic chest pain using machine learning techniques. By analyzing outpatient and follow-up data, the study seeks to enhance the accuracy of diagnosing the underlying causes of chest pain, which can often be complex and varied. The model will be optimized through both retrospective and prospective analyses of large cohort data, ultimately aiming to reduce misdiagnosis and improve treatment pathways for patients experiencing chest pain.
Why it matters
Potential benefit: If successful, this model could significantly improve the diagnostic accuracy and treatment efficiency for patients with acute non-traumatic chest pain.
How similar studies have gone: Other studies utilizing machine learning for diagnostic purposes have shown promise, indicating that this approach may yield beneficial results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 18 years 2. Symptom onset or worsening within 24 hours before presentation, with a chief complaint of acute chest pain meeting the broad definition of chest pain (2021 AHA) 3. Presentation to the emergency department, with a clinical diagnosis consistent with non-traumatic chest pain 4. Signed informed consent Exclusion Criteria: 1. traumatic chest pain 2. systemic pain caused by malignant tumors or rheumatic diseases involving the chest 3. Patients were lost to follow-up
Where it's running
-
Xiaonan He
Beijing, Chaoyang, China Recruiting
Study contacts
- Study coordinator: Xiaonan / He, Professor
- Email: hxndoctor@126.com
- Phone: 15001108399
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.