Mobile Transcranial Magnetic Stimulation for Depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study aims to develop and test a portable Transcranial Magnetic Stimulation (TMS) unit in a van, delivering treatment to patients with treatment-resistant major depression at three locations in South Carolina. The study will recruit up to 30 eligible patients who will receive accelerated TMS sessions over a two-week period. Investigators will assess the feasibility, safety, and efficacy of this mobile treatment approach, with the goal of improving access to TMS for patients who cannot access traditional treatment facilities. The findings will inform future research and potential widespread adoption of mobile TMS units.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult (22-80 years old)
* Have treatment-resistant depression as defined by the e-Mini, and the antidepressant treatment history form (ATHF short).
* Be able to read and communicate in English.
* Able to provide their own consent.
* Access to a computer with videoconferencing ability for initial consent and telescreen.

Exclusion Criteria:

* Patients with unstable medical conditions that might make TMS unsafe. This includes current poorly controlled seizures.
* Ferromagnetic metal in the head.
* Pregnant.
* Currently active substance abuse except tobacco.

Where it's running

• Medical Univerity of South Carolina
  Charleston, South Carolina, United States Recruiting

Study contacts

• Principal investigator: Mark George, MD — Medical University of South Carolina
• Study coordinator: Mark S George, MD
• Email: GEORGEM@MUSC.EDU
• Phone: 8438765142

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.