Mindfulness meditation for older adults with chronic low back pain

Mindfulness-based Meditation for Older Adults With Chronic Low Back Pain Based on the Gut-brain Axis: A Pilot Randomized Controlled Trial

Not applicable Interventional Florida State University · NCT06384001

This study is testing whether mindfulness meditation can help older adults with chronic low back pain feel better and improve their gut health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment66 (estimated)
Ages50 Years to 89 Years
SexAll
SponsorFlorida State University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Tallahassee, Florida)
Trial IDNCT06384001 on ClinicalTrials.gov

What this trial studies

This pilot randomized controlled trial aims to recruit 66 community-dwelling older adults aged 50 and older who experience chronic low back pain. Participants will be assigned to either an active mindfulness-based meditation (MBM) intervention or a sham MBM group for 8 weeks. The study will assess the effects of the MBM intervention on pain levels and symptoms, as well as its impact on the Gut-Brain Axis. The researchers hypothesize that the active intervention will be more effective than the sham group in improving pain and gut microbiota profiles.

Who should consider this trial

Good fit: Ideal candidates are community-dwelling older adults aged 50 and older with moderate chronic low back pain.

Not a fit: Patients with serious underlying illnesses or other chronic pain conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could provide a non-pharmacological approach to managing chronic low back pain in older adults.

How similar studies have performed: Other studies have shown promising results with mindfulness-based interventions for pain management, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. aged 50 years older
2. intact cognition (examined by the Mini-Mental State Exam, ≥ 24)
3. experiencing moderate low back pain daily or almost every day at least the previous three months (≥3 out of 10 on numeric rating scale \[NRS\])
4. able to speak and read English
5. not intent to change medication regimens for pain throughout the trial

Exclusion Criteria:

1. serious underlying illness (e.g., malignant neoplasms, bloodborne illness, low blood platelet count, been in chemotherapy)
2. psychosis
3. function limitation precluded the meditation practice
4. participated meditation program before
5. no access to the internet

Where this trial is running

Tallahassee, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Low Back PainMindfulnessOlder adults
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.