Mindfulness and Vitamin D for Mothers of Preterm Infants

Effects of Maternal Stress on Human Milk Composition and Subsequent Infant Outcomes

Not applicable Interventional University of Idaho · NCT04821544

This study tests if an 8-week mindfulness program and vitamin D supplements can help mothers of preterm infants feel less stressed and improve the quality of their milk.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment500 (estimated)
Ages18 Years to 50 Years
SexFemale
SponsorUniversity of Idaho Academic / other
Locations1 site (Coeur d'Alene, Idaho)
Trial IDNCT04821544 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of an 8-week mindfulness-based intervention focused on self-compassion and vitamin D supplementation on maternal stress and human milk composition in mothers of preterm infants. Participants will be block randomized into three groups: standard care, mindfulness intervention, or vitamin D supplementation. Maternal stress levels and self-compassion will be assessed using validated scales, and biological samples will be collected to analyze changes in human milk and infant health outcomes. The goal is to determine if these interventions can improve maternal well-being and infant health.

Who should consider this trial

Good fit: Ideal candidates for this study are mothers of newborn infants, particularly those with preterm infants, at Kootenai Health NICU and in the Palouse region.

Not a fit: Patients who are not mothers of newborn infants or those who do not have access to the study locations may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance maternal mental health and improve the nutritional quality of human milk, leading to better health outcomes for infants.

How similar studies have performed: Other studies have shown promising results with mindfulness interventions in maternal health, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Mothers of newborn infants at Kootenai Health NICU and the Palouse region

Exclusion Criteria:

\-

Where this trial is running

Coeur d'Alene, Idaho

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postpartum DepressionPreterm LaborMaternal stressMindfulnessHuman milk bioactivesInfant metabolomeMaternal transcriptomeInfant transcriptome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.