Mindful Journey: a smartphone mindfulness program for opioid use disorder and chronic pain

Mindfulness-Based Ecological Momentary Intervention for Co-Occurring Opioid Use Disorder and Chronic Pain: A Pilot Study

Not applicable Interventional Arizona State University · NCT06947122

This project will test whether the Mindful Journey smartphone app can help adults on medication-assisted treatment for opioid use disorder who have chronic pain use brief mindfulness exercises to manage cravings and pain.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment10 (estimated)
Ages18 Years and up
SexAll
SponsorArizona State University Academic / other
Locations2 sites (Phoenix, Arizona and 1 other locations)
Trial IDNCT06947122 on ClinicalTrials.gov

What this trial studies

This pilot interventional project delivers a smartphone-based ecological momentary intervention called Mindful Journey that uses brief, video-based exercises to teach mindful acceptance and savoring skills. The app combines ecological momentary assessments with just-in-time prompts to deliver short mindfulness practices when participants report high-risk moments for craving or pain. The primary focus is on feasibility and acceptability in adults enrolled in medication-assisted treatment for opioid use disorder who report bothersome chronic non-malignant pain. Study procedures occur through sites at Arizona State University with usage, engagement, and preliminary symptom signals tracked over the intervention period.

Who should consider this trial

Good fit: Adults (18+) who are fluent in English, enrolled in medication-assisted treatment for opioid use disorder, report bothersome chronic non-malignant pain, and own a smartphone are ideal candidates.

Not a fit: People with chronic malignant pain or systemic inflammatory disease, those reporting psychotic disorder symptoms, people not in medication-assisted treatment, not fluent in English, or without a smartphone are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the app could give people on medication treatment quick, in-the-moment mindfulness tools to better cope with pain and reduce opioid craving or relapse risk.

How similar studies have performed: Mindfulness-based interventions have shown promise for pain and for substance use separately, but just-in-time smartphone mindfulness interventions specifically targeting co-occurring opioid use disorder and chronic pain are largely novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age or older
* fluent in English
* enrollment in medication-assisted treatment for opioid use disorder
* report at least bothersome chronic pain, as indicated by Graded Chronic Pain Scale-Revised
* has a smartphone.

Exclusion Criteria:

* self-reporting of chronic malignant pain (e.g., cancer) or systemic inflammatory disease (e.g., rheumatoid arthritis, ankylosing spondylitis, lupus, and sarcoidosis)
* self-reporting of psychotic disorder symptoms
* participated in the previous phase of the study in which participants provided feedback to inform the development of the Mindful Journey app.

Where this trial is running

Phoenix, Arizona and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic PainOpioid Use Disordermindfulnessopioid use disorderchronic painmHealthecological momentary intervention
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.