Microbial check of MK1 vs Clip for implant overdentures
Official title: Microbial Evaluation in Patients Wear Double Structure Bars Implant Supported Mandibular Overdentures Attached by Clips or MK-1 Attachments
Run by Mansoura University · NCT07817498 · Data updated 2026-11-12
This study tests whether MK1 attachments or conventional clip attachments lead to different levels of microbial buildup around implant-supported overdentures in adults who are fully toothless.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 65 Years |
| Sex | All |
| Enrollment | 7 (estimated) |
| Sponsor | Mansoura University Academic / other |
| Locations | 1 site (Al Mansurah) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | November 1, 2026 |
| Study ends | January 1, 2027 |
| Registry record updated | September 14, 2026 |
| Trial ID | NCT07817498 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Fully edentulous adults aged 45-65 without systemic conditions affecting implants, with adequate mandibular bone and suitable occlusion to receive four implants.
✕Probably not a fit
Individuals with uncontrolled systemic conditions, parafunctional habits, or mucosal diseases may not benefit from this comparison.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This crossover trial involves seven completely edentulous adults who will receive both MK1 and bar-clip attachment systems for four-implant mandibular overdentures. Each participant serves as their own control, with microbial samples collected from the prosthesis surfaces and peri-implant sites at multiple follow-up points to compare colonization. The study aims to see if attachment type influences microbial accumulation, which could affect maintenance and long-term success. Procedures occur at Mansoura University Faculty of Dentistry, with participants meeting specific inclusion criteria and exclusions to ensure suitability for implant therapy.
Why it matters
Potential benefit: If MK1 or clip attachments show lower microbial buildup, patients could experience easier maintenance and potentially longer-lasting overdenture support.
How similar studies have gone: Previous research in similar attachment comparisons has shown variable effects on microbial colonization, making this study important to clarify because it uses a crossover design.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Completely edentulous patients aged 45-65 years. * Medically healthy patients with no systemic conditions affecting implant placement or osseointegration. * Healthy maxillary and mandibular residual ridges covered by firm mucosa. * Adequate mandibular bone volume in the interforaminal region to receive four implants (minimum 4 mm diameter and 12 mm length), confirmed by CBCT. * Class I maxillomandibular relationship with sufficient interarch space for implant-supported overdentures. Exclusion Criteria: * Uncontrolled diabetes mellitus, immune disorders, osteoporosis, or other contraindications to implant therapy. * Parafunctional habits such as bruxism or clenching. * Flabby ridges or oral mucosal diseases. * Severe temporomandibular joint disorders. * History of allergy to denture or implant materials. * Previous radiotherapy to the head and neck region.
Where it's running
-
Mansoura university faculty of dentistry
Al Mansurah, Egypt Recruiting
Study contacts
- Study coordinator: Mohammed Hussein Raafat abd elfatah
- Email: mohammed.hussein@mans.edu.eg
- Phone: +201092663488
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.