Method to identify intersegmental planes in lung cancer surgery
Application of Partial Pressure of Oxygen Control Method in Fast Identification of Intersegmental Plane in Anatomical Sublobar Resection: a Prospective, Randomized Controlled Study
This study tests a new method to help doctors find the right areas to remove during lung cancer surgery, aiming to improve outcomes for patients with small tumors.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Tang-Du Hospital Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT06644066 on ClinicalTrials.gov |
What this trial studies
This study investigates a novel approach using the Partial Pressure of Oxygen Control method to enhance the identification of intersegmental planes during sublobar resection for early-stage non-small cell lung cancer (NSCLC). The method aims to improve surgical outcomes by facilitating quicker and more accurate identification of these planes, which is crucial for preserving lung function. Participants will undergo this intervention to assess its effectiveness compared to traditional methods. The study targets patients with small tumors detected through CT screening.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 with early-stage NSCLC and a maximum tumor diameter of 2.0 cm.
Not a fit: Patients with a history of lung surgery or severe pulmonary conditions such as interstitial pneumonia or emphysema may not benefit from this study.
Why it matters
Potential benefit: If successful, this method could lead to improved surgical precision and better preservation of lung function for patients undergoing surgery for lung cancer.
How similar studies have performed: While the approach is innovative, similar studies have shown promise in improving surgical techniques for lung cancer, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Between the ages of 18 and 75; 2. Gender unlimited; 3. Eastern Cooperative Oncology Group（ECOG） Performance status（PS） score 0-1 points; 4. Thin slice CT indicates that the maximum tumor diameter is ≤ 2.0cm and 0 ≤ CTR\<1.0; （Consolidation Tumor Ratio，CTR） 5. Those who voluntarily sign the informed consent form for research can comply with the requirements of the research visit plan and other protocols. Exclusion Criteria: 1. Individuals with a history of lung surgery in the past; 2. Patients with interstitial pneumonia, pulmonary alveoli, pulmonary fibrosis, or severe emphysema; 3. Those who undergo chest surgery due to various reasons or change the surgical plan during the operation; 4. The subjects do not understand, cooperate or refuse to sign the informed consent form regarding the research protocol.
Where this trial is running
Xi'an, Shaanxi
- The Second Affiliated Hospital of the Air Force Medical University of PLA — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Study coordinator: Xiaolong Yan, MD
- Email: yanxiaolong@fmmu.edu.cn
- Phone: 15991269383
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.