Measuring swallowing difficulties after thyroid surgery
Official title: Dysphagia After Thyroidectomy
Run by Istituto Auxologico Italiano · NCT06296420 · Data updated 2026-11-12
This study is trying to create a questionnaire to help people who have had thyroid surgery or have a goiter report their swallowing and throat discomfort symptoms better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 420 (estimated) |
| Sponsor | Istituto Auxologico Italiano Academic / other |
| Locations | 1 site (Milan, MI) |
| Status | Recruiting |
| Started | January 31, 2024 |
| Main results expected | November 30, 2026 |
| Study ends | November 30, 2026 |
| Registry record updated | December 18, 2025 |
| Trial ID | NCT06296420 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with goiter or those who have undergone thyroidectomy.
✕Probably not a fit
Patients with neurological disorders or other conditions affecting the aerodigestive tract that could cause swallowing issues may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to develop a questionnaire that accurately measures swallowing and throat discomfort symptoms in patients with goiter or those who have undergone thyroidectomy. The questionnaire will be created using the Rasch model to ensure it meets essential measurement criteria such as unidimensionality and generalizability. Initially, interviews will be conducted with affected patients to identify relevant items and response categories, followed by administering the questionnaire to patients before and after their surgery to assess changes in symptoms. Additionally, the study will evaluate the psychological effects of goiter and thyroidectomy, as well as the characteristics of surgical scars.
Why it matters
Potential benefit: If successful, this study could provide a reliable tool for clinicians to assess and improve the quality of life for patients experiencing swallowing difficulties after thyroid surgery.
How similar studies have gone: While this approach is focused on developing a specific measurement tool, similar studies have successfully utilized psychometric methods to assess patient-reported outcomes in other medical conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of goiter or thyroidectomy. Exclusion Criteria: * Diagnosis of other neurological disorders or disorders involving the aerodigestive tract that could cause swallowing disorders. * Previous surgery of the neck or involving the aerodigestive tract.
Where it's running
-
IRCCS Istituto Auxologico Italiano
Milan, Mi, Italy Recruiting
Study contacts
- Principal investigator: Stefano Scarano, MD — University of Milan, IRCCS Istituto Auxologico Italiano
- Study coordinator: Stefano Scarano, MD
- Email: s.scarano@auxologico.it
- Phone: +3902619116717
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
ETHY-001 safety and activity in Thyroid Eye Disease (TED)
This study tests ETHY-001 versus placebo to see if it is safe, tolerable, and shows activity in people with thyroid eye disease.
-
How thyroid problems affect liver blood tests
This observational study will see if adults aged 20–60 with treated, untreated, or newly diagnosed hypo- or hyperthyroidism have different liver blood test results compared with healthy euthyroid controls.
-
Right blood level of ciprofol for anesthesia during thyroid surgery
This test looks at ciprofol blood levels to see what keeps adults aged 18–65 safely unconscious during elective thyroidectomy.
-
Impact of thyroid surgery on sleep apnea in goiter patients
This study looks at how thyroid surgery affects sleep apnea in people with goiters to see if it helps them breathe better while sleeping.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.