Measuring muscle strength in critically ill patients and healthy individuals in Brazil
Analysis of Peripheral Muscle Strength Measurement Methods in Healthy Individuals and Critical Patients: A Health Technology Assessment
This study is trying to find out how strong muscles are in critically ill patients and healthy people in Brazil to help set standard measures for muscle strength.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 180 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | University of Pernambuco Academic / other |
| Locations | 4 sites (Recife, Brazil and 3 other locations) |
| Trial ID | NCT06296381 on ClinicalTrials.gov |
What this trial studies
This observational study aims to establish normative values for peripheral muscle strength in both critically ill patients and healthy individuals in Brazil. It will involve adult and elderly participants, assessing muscle strength using handheld dynamometers and evaluating mobility status in ICU patients. The study will also collect secondary data from medical records to correlate muscle strength with various health indicators. The goal is to create standardized reference equations and cutoff points for different demographics.
Who should consider this trial
Good fit: Ideal candidates include adults and elderly individuals aged 18 to 90, both healthy and those admitted to the ICU without recent muscle injuries.
Not a fit: Patients with severe osteoporosis, neuromuscular diseases, or those unable to follow commands may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide critical benchmarks for assessing muscle strength in patients, potentially improving outcomes in critical care settings.
How similar studies have performed: While similar studies have been conducted, this specific approach to establish normative values for the Brazilian population is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy individuals of both sexes * Patients and volunteers aged between 18 and 90 years old (youth/adults/elderly). * Patients admitted to the ICU. * No recent muscle injuries of both limbs for a past 6-months. Exclusion Criteria: Patients and volunteers \< 20 years and \> 90 years Healthy individuals * Unable to follow command completely * Severe osteoporosis or neuromuscular disease leading to decreased muscle strength * Presence of opened or infectious wound * Presence of pain in evaluating muscle groups Patients in ICU * Unable to follow command completely * Acute stroke * Hip fracture, unstable cervical spine or pathological fracture * Recent surgery involving the upper airways, chest, abdomen, or limbs * Presence of opened or infectious wound * Presence of pain in evaluating muscle groups
Where this trial is running
Recife, Brazil and 3 other locations
- Complexo Hospitalar Unimed Recife - CHUR — Recife, Brazil, Brazil (Recruiting)
- Federal University of Pernambuco (UFPE) — Recife, Pernambuco, Brazil (Recruiting)
- Hospital Otávio de Freitas — Recife, Pernambuco, Brazil (Recruiting)
- Hospital Nossa Senhora das Graças — Recife, Pernambuco, Brazil (Active_not_recruiting)
Study contacts
- Principal investigator: Pedro Vinicius Porfirio — University of Pernambuco
- Study coordinator: Shirley Campos
- Email: shirley.campos@ufpe.br
- Phone: +55 81 9941-3087
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.