Measuring kidney blood flow changes in critically ill patients on dialysis.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between changes in the renal resistive index (RRI) and the recovery of kidney function in critically ill patients undergoing continuous renal replacement therapy (CRRT) for acute kidney injury (AKI). By utilizing Doppler ultrasound measurements to assess RRI, the study seeks to identify earlier indicators of kidney dysfunction compared to traditional markers like serum creatinine. The findings could enhance monitoring strategies for AKI in intensive care settings, potentially improving patient outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All ICU patients undergoing CRRT due to AKI

Exclusion Criteria:

* age \<18 years
* pregnancy
* history of chronic kidney disease in stage 4 or 5
* post-kidney transplant status
* mechanical circulatory support
* occurrence of one or more conditions preventing reliable RRI measurement in both kidneys:

  * challenging technical conditions of ultrasound examination, hindering proper visualization of the kidney
  * post-kidney injury in grade III and higher, according to AAST
  * advanced parenchymal kidney pathology: atrophy, hypoplasia, cirrhosis, extensive ischemia (more than 2/3 of the parenchyma),
  * kidney diseases preventing parenchyma identification: advanced cancer (stage above T1 according to TNM), certain forms of polycystic kidney disease
  * inflammatory kidney diseases
  * obstructive uropathy
  * renal vascular pathologies: renal vein thrombosis, significant stenosis (\>60%), and renal artery occlusion.

Where it's running

• Department of Anesthesiology and Intensive Care, Uniwersytecki Szpital Kliniczny w Opolu
  Opole, Opole Voivodeship, Poland Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.