Measuring bottom-of-foot pressures in people with lateral forefoot amputation due to diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study measures plantar pressures in adults with healed unilateral lateral forefoot amputation to identify high-pressure regions and analyze walking patterns. Data will be used to understand biomechanical factors linked to diabetic ulcers and reamputation risk. Findings could inform footwear and insole design to reduce pressure-related injuries. The study focuses on real-world walking to capture clinically relevant pressure patterns.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 21 years
* Diagnosed with type 2 diabetes
* Presence of a healed unilateral lateral forefoot amputation (at least 5th MPJ, up to any level including the 2nd toe and 2nd ray)
* Ability to walk 10 meters unaided or with simple devices
* Of sound mind to communicate, follow instructions, and consent independently
* English or Chinese speaking

Exclusion Criteria:

* Amputation or partial amputation of the hallux and any bones higher than midfoot (cuneiforms, cuboid, navicular, calcaneus) on the affected foot
* Major lower limb amputation (above ankle), of other leg
* Severe gait impairments unrelated to foot amputation (stroke, foot drop etc)
* Other foot deforming disease such as, but not limited to, charcot neuroarthropathy, rheumatoid arthritis etc.

Where it's running

• National University Hospital
  Singapore, Singapore Recruiting
• Ng Teng Fong General Hospital
  Singapore, Singapore Recruiting

Study contacts

• Study coordinator: Xi Chen, Bachelor of Podiatry
• Email: chen_xi@nuhs.edu.sg
• Phone: +6589732316

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.