Measuring antioxidant activity and oxidative stress in patients undergoing eye surgery
Effects of Laser Species and Ocular Antioxidant Activity on Postoperative Inflammation, Oxidative Stress and Visual Prognosis in Patients Undergoing Ophthalmic Surgery - a Comparative Study.
This study is testing if new laser eye surgeries can help patients recover better by looking at their eye stress and antioxidant levels after the procedures.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital Academic / other |
| Locations | 2 sites (Taipei and 1 other locations) |
| Trial ID | NCT06743594 on ClinicalTrials.gov |
What this trial studies
This observational trial investigates the effects of novel laser refractive surgery techniques and laser-assisted cataract surgery on postoperative inflammation and recovery by measuring oxidative stress levels. It aims to assess total reactive oxygen species, antioxidant capacity, and ascorbic acid in the eyes of patients undergoing these procedures. All participants will undergo a series of eye examinations to evaluate their visual acuity, intraocular pressure, and other ocular metrics. The study seeks to determine if new laser technologies are beneficial for patients with low antioxidant activity.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 and older who are scheduled for corneal refractive surgery or cataract surgery.
Not a fit: Patients with eye infections, severe retinal diseases, or significant eye injuries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved recovery and reduced inflammation for patients undergoing ophthalmic surgeries.
How similar studies have performed: While the approach of measuring oxidative stress in surgical patients is not widely tested, similar studies have shown promising results in other surgical contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * at least 20 years old * corneal refractive surgery or cataract surgery patients Exclusion Criteria: * patients with eye infections * presence of severe retinal disease * presence of severe eye injury or severe ptosis
Where this trial is running
Taipei and 1 other locations
- Taipei Nobel Eye Clinic — Taipei, Taiwan (Recruiting)
- Chang Gung Memorial Hospital — Taoyuan, Taiwan (Recruiting)
Study contacts
- Study coordinator: Hung-Chi Chen, PhD
- Email: mr3756@cgmh.org.tw
- Phone: +886-975365859
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.