Mapping brain functions in epilepsy patients
Official title: Intracranial Stimulation Mapping In Epilepsy -The InStim Study
Run by University of Minnesota · NCT05290610 · Data updated 2026-11-12
This study is trying to create brain maps to see how different parts of the brain work together in adults with partial epilepsy to help improve surgery results.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Status | Recruiting |
| Started | June 1, 2022 |
| Main results expected | June 1, 2027 |
| Study ends | September 1, 2027 |
| Registry record updated | April 9, 2026 |
| Trial ID | NCT05290610 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are undergoing intracranial EEG monitoring for epilepsy surgery.
✕Probably not a fit
Patients who are pregnant or have cognitive impairments that prevent them from understanding the study may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to assess the feasibility of creating brain maps that identify cerebral functions and the flow of information between brain regions in adults with partial epilepsy. Participants will be individuals who are already undergoing intracranial EEG monitoring as part of their clinical care for epilepsy surgery planning. The study will involve functional mapping techniques to gather data on brain activity and connectivity. By understanding these patterns, researchers hope to improve surgical outcomes for epilepsy patients.
Why it matters
Potential benefit: If successful, this study could enhance the precision of epilepsy surgeries, leading to better seizure control and improved quality of life for patients.
How similar studies have gone: While this approach is innovative, similar studies focusing on brain mapping in epilepsy have shown promise in improving surgical outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female 18 years and older at screening. * Written informed consent is obtained from the participant to comply with the requirements of the study. * Stated willingness to comply with all study procedures and availability for the duration of the study * Currently undergoing clinically indicated intracranial EEG monitoring for planning of epilepsy surgery in the University of Minnesota/MINCEP program. Exclusion Criteria: * Pregnancy ruled out prior to approval for intracranial EG monitoring. * Persons who are rendered temporarily or permanently invulnerable by inability to understand the research due to study complexity, cognitive impairment, or by inability to make independent decisions owing to University of Minnesota or to Fairview health services.
Where it's running
-
University of Minnesota
Minneapolis, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Alexander Herman, MD — Umn
- Study coordinator: Matthew Maple
- Email: maple036@umn.edu
- Phone: 612-946-1424
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.