Mapping brain functions in epilepsy patients
Intracranial Stimulation Mapping In Epilepsy -The InStim Study
This study is trying to create brain maps to see how different parts of the brain work together in adults with partial epilepsy to help improve surgery results.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT05290610 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the feasibility of creating brain maps that identify cerebral functions and the flow of information between brain regions in adults with partial epilepsy. Participants will be individuals who are already undergoing intracranial EEG monitoring as part of their clinical care for epilepsy surgery planning. The study will involve functional mapping techniques to gather data on brain activity and connectivity. By understanding these patterns, researchers hope to improve surgical outcomes for epilepsy patients.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are undergoing intracranial EEG monitoring for epilepsy surgery.
Not a fit: Patients who are pregnant or have cognitive impairments that prevent them from understanding the study may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the precision of epilepsy surgeries, leading to better seizure control and improved quality of life for patients.
How similar studies have performed: While this approach is innovative, similar studies focusing on brain mapping in epilepsy have shown promise in improving surgical outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female 18 years and older at screening. * Written informed consent is obtained from the participant to comply with the requirements of the study. * Stated willingness to comply with all study procedures and availability for the duration of the study * Currently undergoing clinically indicated intracranial EEG monitoring for planning of epilepsy surgery in the University of Minnesota/MINCEP program. Exclusion Criteria: * Pregnancy ruled out prior to approval for intracranial EG monitoring. * Persons who are rendered temporarily or permanently invulnerable by inability to understand the research due to study complexity, cognitive impairment, or by inability to make independent decisions owing to University of Minnesota or to Fairview health services.
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Alexander Herman, MD — Umn
- Study coordinator: Matthew Maple
- Email: maple036@umn.edu
- Phone: 612-946-1424
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.