Mapping brain function in epilepsy patients
Functional Brain Mapping in Pediatric Neurosurgery
This study is testing a new brain mapping technique to see if it can help doctors better plan epilepsy surgery and improve language outcomes for patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 6 Months to 21 Years |
| Sex | All |
| Sponsor | Wayne State University Academic / other |
| Locations | 2 sites (Detroit, Michigan and 1 other locations) |
| Trial ID | NCT05755919 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate a new brain mapping technique called 'six-dimensional dynamic tractography' for patients undergoing epilepsy surgery. The approach visualizes neural activity and the connections between brain regions that support language processing. By using advanced electrophysiology biomarkers, the study seeks to improve predictions of language outcomes after surgery. The goal is to enhance the understanding of brain dynamics related to language and optimize surgical planning for epilepsy patients.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for epilepsy surgery who will undergo intracranial EEG recording.
Not a fit: Patients with malignant brain tumors or progressive neurodegenerative disorders will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better surgical outcomes and improved language function for epilepsy patients.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving surgical outcomes through advanced brain mapping techniques.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Epilepsy surgery with extraoperative intracranial EEG recording with subdural or depth electrodes. Exclusion Criteria: * Patients with a malignant brain tumor, or progressive neurodegenerative or metabolic disorders who are not considered candidates for intracranial EEG recording.
Where this trial is running
Detroit, Michigan and 1 other locations
- Children's Hospital of Michigan — Detroit, Michigan, United States (Recruiting)
- Wayne State University — Detroit, Michigan, United States (Recruiting)
Study contacts
- Principal investigator: Eishi Asano, MD, PhD — Wayne State University
- Study coordinator: Eishi Asano, MD, PhD
- Email: easano@med.wayne.edu
- Phone: 313-745-5563
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.