Mapping brain function in epilepsy patients
Official title: Functional Brain Mapping in Pediatric Neurosurgery
Run by Wayne State University · NCT05755919 · Data updated 2026-11-12
This study is testing a new brain mapping technique to see if it can help doctors better plan epilepsy surgery and improve language outcomes for patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Months to 21 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Wayne State University Academic / other |
| Locations | 2 sites (Detroit, Michigan and 1 other locations) |
| Status | Recruiting |
| Started | May 16, 2022 |
| Main results expected | February 28, 2027 |
| Study ends | March 31, 2027 |
| Registry record updated | February 26, 2025 |
| Trial ID | NCT05755919 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients scheduled for epilepsy surgery who will undergo intracranial EEG recording.
✕Probably not a fit
Patients with malignant brain tumors or progressive neurodegenerative disorders will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate a new brain mapping technique called 'six-dimensional dynamic tractography' for patients undergoing epilepsy surgery. The approach visualizes neural activity and the connections between brain regions that support language processing. By using advanced electrophysiology biomarkers, the study seeks to improve predictions of language outcomes after surgery. The goal is to enhance the understanding of brain dynamics related to language and optimize surgical planning for epilepsy patients.
Why it matters
Potential benefit: If successful, this study could lead to better surgical outcomes and improved language function for epilepsy patients.
How similar studies have gone: While this approach is innovative, similar studies have shown promise in improving surgical outcomes through advanced brain mapping techniques.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Epilepsy surgery with extraoperative intracranial EEG recording with subdural or depth electrodes. Exclusion Criteria: * Patients with a malignant brain tumor, or progressive neurodegenerative or metabolic disorders who are not considered candidates for intracranial EEG recording.
Where it's running
-
Children's Hospital of Michigan
Detroit, Michigan, United States Recruiting -
Wayne State University
Detroit, Michigan, United States Recruiting
Study contacts
- Principal investigator: Eishi Asano, MD, PhD — Wayne State University
- Study coordinator: Eishi Asano, MD, PhD
- Email: easano@med.wayne.edu
- Phone: 313-745-5563
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.