Clinical trial Recruiting at 2 sites Interventional Ages 6 Months to 21

Mapping brain function in epilepsy patients

Official title: Functional Brain Mapping in Pediatric Neurosurgery

Run by Wayne State University · NCT05755919 · Data updated 2026-11-12

This study is testing a new brain mapping technique to see if it can help doctors better plan epilepsy surgery and improve language outcomes for patients.

Quick facts

Study typeInterventional
Ages6 Months to 21 Years
SexAll
Enrollment80 (estimated)
SponsorWayne State University
Academic / other
Locations2 sites (Detroit, Michigan and 1 other locations)
StatusRecruiting
StartedMay 16, 2022
Main results expectedFebruary 28, 2027
Study endsMarch 31, 2027
Registry record updatedFebruary 26, 2025
Trial IDNCT05755919 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients scheduled for epilepsy surgery who will undergo intracranial EEG recording.

Probably not a fit

Patients with malignant brain tumors or progressive neurodegenerative disorders will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate a new brain mapping technique called 'six-dimensional dynamic tractography' for patients undergoing epilepsy surgery. The approach visualizes neural activity and the connections between brain regions that support language processing. By using advanced electrophysiology biomarkers, the study seeks to improve predictions of language outcomes after surgery. The goal is to enhance the understanding of brain dynamics related to language and optimize surgical planning for epilepsy patients.

Why it matters

Potential benefit: If successful, this study could lead to better surgical outcomes and improved language function for epilepsy patients.

How similar studies have gone: While this approach is innovative, similar studies have shown promise in improving surgical outcomes through advanced brain mapping techniques.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Epilepsy surgery with extraoperative intracranial EEG recording with subdural or depth electrodes.

Exclusion Criteria:

* Patients with a malignant brain tumor, or progressive neurodegenerative or metabolic disorders who are not considered candidates for intracranial EEG recording.

Where it's running

  • Children's Hospital of Michigan
    Detroit, Michigan, United States
    Recruiting
  • Wayne State University
    Detroit, Michigan, United States
    Recruiting

Study contacts

  • Principal investigator: Eishi Asano, MD, PhD — Wayne State University
  • Study coordinator: Eishi Asano, MD, PhD
  • Email: easano@med.wayne.edu
  • Phone: 313-745-5563

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.