MAP- or Cardiac Index-Guided Hemodynamic Management in Colorectal Surgery
Official title: Comparison of the Effects of Mean Arterial Pressure-Based and Cardiac Index-Based Intraoperative Hemodynamic Management on Postoperative Renal Function in Patients Undergoing Colorectal Surgery: A Prospective Randomized Study
Run by Ankara Etlik City Hospital · NCT07609680 · Data updated 2026-11-12
In people undergoing colorectal surgery, this study tests whether guiding intraoperative blood pressure with mean arterial pressure or with cardiac index leads to better kidney function after surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Ankara Etlik City Hospital Government |
| Locations | 1 site (Ankara, Yenimahalle\Ankara) |
| Status | Recruiting |
| Started | June 2, 2026 |
| Main results expected | December 14, 2027 |
| Study ends | December 28, 2027 |
| Registry record updated | June 3, 2026 |
| Trial ID | NCT07609680 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 with ASA physical status II–III and an estimated GFR ≥60 mL/min/1.73 m² scheduled for colorectal surgery who can provide informed consent.
✕Probably not a fit
Patients with preoperative kidney disease (eGFR <60), higher ASA status, or those not meeting the eligibility criteria may not see a benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective randomized trial compares two intraoperative hemodynamic strategies in colorectal surgery patients. Participants are randomly assigned to MAP-guided or cardiac index-guided management to maintain circulatory adequacy during surgery. The primary outcome is the change in serum creatinine from baseline, reflecting early postoperative renal function. By focusing on hemodynamic targets beyond blood pressure alone, the study aims to determine which approach better preserves renal perfusion during major abdominal procedures. The trial is conducted at Ankara Etlik City Hospital and includes adults 18 to 80 without significant preoperative kidney impairment.
Why it matters
Potential benefit: If successful, the approach that better preserves renal function could reduce postoperative kidney complications and improve recovery after colorectal surgery.
How similar studies have gone: Previous work suggests hemodynamic management strategies can impact organ perfusion, but direct comparisons of MAP versus cardiac index guidance in colorectal surgery are not yet established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 to 80 years * Patients with American Society of Anesthesiologists physical status II-III * Patients with estimated glomerular filtration rate ≥60 mL/min/1.73 m² * Patients scheduled for colorectal surgery * Patients who provide written informed consent Exclusion Criteria: * Patients younger than 18 years or older than 80 years * Patients with estimated glomerular filtration rate \<60 mL/min/1.73 m² * Patients with American Society of Anesthesiologists physical status other than II-III * Patients who refuse to participate in the study * Patients who withdraw consent at any stage of the study
Where it's running
-
Ankara Etlik City Hospital
Ankara, Yenimahalle\Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: İbrahim MD Topcu
- Email: ibrahimtpc78@gmail.com
- Phone: 00905437860316
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.