Mammography Texture Features in Women and AI
Official title: A Cohort Study on feMale Patients' mammogRaphic texturE featureS: the COMPRESS Trial
Run by Tampere University Hospital · NCT06469606 · Data updated 2026-11-12
This study tests an AI tool to help interpret mammograms for women needing mastectomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 200 (estimated) |
| Sponsor | Tampere University Hospital Academic / other |
| Locations | 1 site (Tampere) |
| Status | Recruiting |
| Started | June 17, 2024 |
| Main results expected | December 15, 2035 |
| Study ends | December 15, 2038 |
| Registry record updated | August 5, 2026 |
| Trial ID | NCT06469606 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Biological females aged 18 or older with a clinical indication for unilateral or bilateral mastectomy who can provide informed consent.
✕Probably not a fit
Patients without an indication for mastectomy or those unable to benefit from AI-assisted interpretation may not experience direct benefits.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study investigates how radiomics texture features from mammography relate to clinical and biological factors in female patients. It uses an AI-based tool to support clinical decision-making in the context of mastectomy indications. The goal is to understand how imaging parameters and biology influence texture features and to translate these findings into robust AI-assisted practice. The study will examine the interplay between imaging, clinical data, and biology to improve consistency and usefulness of AI outputs. No phase information is provided for this intervention.
Why it matters
Potential benefit: If successful, the AI tool could improve consistency and accuracy of mammography interpretation to guide treatment decisions.
How similar studies have gone: Previous radiomics studies in mammography have shown promise in risk assessment and lesion detection, but translation to routine practice remains challenging and is under active investigation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Candidate is a biological female aged 18 years or above; * Candidate is willing and able to give informed consent and gives their written consent for the participation in the study; * There is a clinical indication for a uni- or bilateral mastectomy Exclusion Criteria: * Candidate lacks the capacity to provide informed consent; * Candidate has breast implants
Where it's running
-
Wellbeing Services County of Pirkanmaa
Tampere, Finland Recruiting
Study contacts
- Study coordinator: Otso Arponen, MD, PhD
- Email: otso.arponen@tuni.fi
- Phone: +3583311611
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.